Network pharmacology reveals potential functional components and underlying molecular mechanisms of Andrographis paniculata in esophageal cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7411
Abstract: Antitumor and antimetastatic effects of the medicinal herb Andrographis paniculata (AP) in esophageal cancer (EC) have been previously reported. In this study, we aimed to uncover the potential functional components and the underlying molecular mechanisms… read more here.
Keywords: pharmacology; functional components; molecular mechanisms; underlying molecular ... See more keywords
Conservation of adaptive potential and functional diversity
Sign Up to like & getrecommendations! Published in 2019 at "Conservation Genetics"
DOI: 10.1007/s10592-019-01151-x
Abstract: The conservation of adaptive potential to enable populations and species to respond to environmental change is one of the cornerstones of conservation genetics. To date, however, most work has by necessity focused on neutral markers… read more here.
Keywords: conservation adaptive; genetics; functional diversity; conservation ... See more keywords
Tapping into the coordinative potential of a C-functional 1,4-diphosphabarrelene using two sets of complementary ligand centres.
Sign Up to like & getrecommendations! Published in 2024 at "Dalton transactions"
DOI: 10.1039/d4dt01817f
Abstract: 7,8-Dihydro-1,4-diphosphabarrelene diselones and bis(NHCs) were synthesised and employed as multitopic P,Se and P,C ligands in coordination chemistry, benefitting from a unique bent, P-bridged topology, thus being promising new building blocks. read more here.
Keywords: tapping coordinative; functional diphosphabarrelene; diphosphabarrelene; coordinative potential ... See more keywords
Abstract 1595: Functional genomic analysis of 18q21.1 locus identifies potential functional variants and genes for colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Epidemiology"
DOI: 10.1158/1538-7445.am2019-1595
Abstract: Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in the world. Genome-wide association studies have identified approximately 50 genetic risk loci for CRC. We have previously identified SNP rs7229639, located in the… read more here.
Keywords: potential functional; locus; cancer; gene ... See more keywords
Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010050
Abstract: Genome-wide association studies (GWAS) have identified more than 160 susceptibility loci for colorectal cancer (CRC). The effects of these variants, particularly their mechanisms, however, remain unclear. In this study, a comprehensive functional annotation of CRC-related… read more here.
Keywords: functional variants; identification potential; potential functional; crc ... See more keywords
Exploring the antioxidant and anti-cancer potential of functional foods from vegetal waste: a path to sustainability
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Food Engineering"
DOI: 10.1515/ijfe-2024-0248
Abstract: Abstract This work examines the potential of functional foods derived from vegetal waste, focusing on their antioxidant and anti-cancer properties. By-products such as fruit peels, seeds, stems, and leaves, typically discarded during agricultural activities and… read more here.
Keywords: cancer; antioxidant anti; waste; vegetal waste ... See more keywords
Okra (Abelmoschus esculentus L.) as a Potential Functional Food Source of Mucilage and Bioactive Compounds with Technological Applications and Health Benefits
Sign Up to like & getrecommendations! Published in 2021 at "Plants"
DOI: 10.3390/plants10081683
Abstract: Abelmoschus esculentus has fruit popularly known as okra and belongs to the Malvaceae family. It is commonly used in cooking but also in traditional medicine in the treatment of worms, dysentery, inflammation, and also irritation… read more here.
Keywords: functional food; abelmoschus esculentus; mucilage; potential functional ... See more keywords
Molecular insight into the potential functional role of pseudoenzyme GFOD1 via interaction with NKIRAS2
Sign Up to like & getrecommendations! Published in 2024 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2024105
Abstract: The glucose-fructose oxidoreductase/inositol dehydrogenase/rhizopine catabolism protein (Gfo/Idh/MocA) family includes a variety of oxidoreductases with a wide range of substrates that utilize NAD or NADP as redox cofactor. Human contains two members of this family, namely… read more here.
Keywords: pseudoenzyme; molecular insight; functional role; gfod1 ... See more keywords