Network pharmacology reveals potential functional components and underlying molecular mechanisms of Andrographis paniculata in esophageal cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7411
Abstract: Antitumor and antimetastatic effects of the medicinal herb Andrographis paniculata (AP) in esophageal cancer (EC) have been previously reported. In this study, we aimed to uncover the potential functional components and the underlying molecular mechanisms… read more here.
Keywords: pharmacology; functional components; molecular mechanisms; underlying molecular ... See more keywords
Conservation of adaptive potential and functional diversity
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DOI: 10.1007/s10592-019-01151-x
Abstract: The conservation of adaptive potential to enable populations and species to respond to environmental change is one of the cornerstones of conservation genetics. To date, however, most work has by necessity focused on neutral markers… read more here.
Keywords: conservation adaptive; genetics; functional diversity; conservation ... See more keywords
Abstract 1595: Functional genomic analysis of 18q21.1 locus identifies potential functional variants and genes for colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Epidemiology"
DOI: 10.1158/1538-7445.am2019-1595
Abstract: Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in the world. Genome-wide association studies have identified approximately 50 genetic risk loci for CRC. We have previously identified SNP rs7229639, located in the… read more here.
Keywords: potential functional; locus; cancer; gene ... See more keywords
Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer
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DOI: 10.1371/journal.pgen.1010050
Abstract: Genome-wide association studies (GWAS) have identified more than 160 susceptibility loci for colorectal cancer (CRC). The effects of these variants, particularly their mechanisms, however, remain unclear. In this study, a comprehensive functional annotation of CRC-related… read more here.
Keywords: functional variants; identification potential; potential functional; crc ... See more keywords
Okra (Abelmoschus esculentus L.) as a Potential Functional Food Source of Mucilage and Bioactive Compounds with Technological Applications and Health Benefits
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DOI: 10.3390/plants10081683
Abstract: Abelmoschus esculentus has fruit popularly known as okra and belongs to the Malvaceae family. It is commonly used in cooking but also in traditional medicine in the treatment of worms, dysentery, inflammation, and also irritation… read more here.
Keywords: functional food; abelmoschus esculentus; mucilage; potential functional ... See more keywords