Design, synthesis and biological evaluation of novel 2,3-dihydroquinazolin- 4(1H)-one derivatives as potential fXa inhibitors.
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DOI: 10.1016/j.ejmech.2016.09.055
Abstract: Coagulation factor Xa (fXa) is a particularly attractive target for the development of effective and safe anticoagulants. In this study, novel 2,3-dihydroquinazolin-4(1H)-one derivatives were designed as potential fXa inhibitors based on anthranilamide structure which has… read more here.
Keywords: fxa inhibitors; fxa; one derivatives; dihydroquinazolin one ... See more keywords