The potential of interleukin-37 as an effective therapeutic agent in asthma
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DOI: 10.1186/s12931-017-0675-x
Abstract: Interleukin (IL)-37 belongs to the IL-1 cytokine family. It binds to IL-18Rα and recruits the orphan decoy IL-1R8. Emerging evidence shows that IL-37 is a key player in the regulation of inflammation, cellular differentiation, and… read more here.
Keywords: inflammation; inflammatory; effective therapeutic; asthma ... See more keywords
Identification of potential interleukin-8 inhibitors acting on the interactive site between chemokine and CXCR2 receptor: A computational approach
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DOI: 10.1371/journal.pone.0264385
Abstract: Interactions between interleukin (IL)-8 and its receptors, CXCR1, and CXCR2, serve crucial roles in inflammatory conditions and various types of cancers. Inhibition of this signaling pathway has been exploited as a promising strategy in treating… read more here.
Keywords: potential interleukin; inhibitors acting; site; identification potential ... See more keywords
Potential of Interleukin (IL)-12 Group as Antivirals: Severe Viral Disease Prevention and Management
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DOI: 10.3390/ijms24087350
Abstract: The interleukin (IL)-12 family consists of pro- and anti-inflammatory cytokines that are able to signal the activation of host antiviral immunity while preventing over-reactive immune reactions due to active virus replication and viral clearance. Amongst… read more here.
Keywords: group antivirals; virus infections; potential interleukin; interleukin group ... See more keywords