Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond
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DOI: 10.3390/genes13122181
Abstract: R-loops are DNA–RNA hybrids that play multifunctional roles in gene regulation, including replication, transcription, transcription–replication collision, epigenetics, and preserving the integrity of the genome. The aberrant formation and accumulation of unscheduled R-loops can disrupt gene… read more here.
Keywords: potential loops; role; diagnostic potential; loops cancer ... See more keywords