COL4A1 mutations as a potential novel cause of autosomal dominant CAKUT in humans
Sign Up to like & getrecommendations! Published in 2019 at "Human Genetics"
DOI: 10.1007/s00439-019-02042-4
Abstract: Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease (~ 45%) that manifests before 30 years of age. The genetic locus containing COL4A1 (13q33–34) has been implicated in… read more here.
Keywords: potential novel; cause; col4a1 mutations; cakut ... See more keywords
Cytotoxic Potential of Novel Bacillary Ribonucleases Balnase and Balifase
Sign Up to like & getrecommendations! Published in 2020 at "BioNanoScience"
DOI: 10.1007/s12668-020-00720-6
Abstract: In this work, a comparative analysis of structural organization and biological activity of low-molecular weight ribonucleases (RNases) secreted by Bacillus altitudinis (balnase) and B. licheniformis (balifase) with Bacillus pumilus RNase binase was performed. All three… read more here.
Keywords: potential novel; balifase; balnase balifase; novel bacillary ... See more keywords
Structural characterization and antioxidant potential of a novel anionic exopolysaccharide produced by marine Microbacterium aurantiacum FSW-25.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.03.016
Abstract: An exopolysaccharide (EPS) producing strain FSW-25 was isolated from the Rasthakaadu beach Kanyakumari, Tamil Nadu India. Based on polyphasic taxonomy, the strain FSW-25 was assigned to the genus Microbacterium and found to be the closest… read more here.
Keywords: potential novel; novel anionic; characterization antioxidant; structural characterization ... See more keywords
Allergenic potential of novel proteins – What can we learn from animal production?
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.07.024
Abstract: &NA; Currently, risk assessment of the allergenic potential of novel proteins relies heavily on evaluating protein digestibility under normal conditions based on the theory that allergens are more resistant to gastrointestinal digestion than non‐allergens. There… read more here.
Keywords: potential novel; production; novel proteins; allergenic potential ... See more keywords
Antibacterial Potential of Novel Acetamide Derivatives of 2-Mercaptobenzothiazole: Synthesis and Docking Studies
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c05782
Abstract: 2-Mercaptobenzothiazole and its derivatives are widely known for their diverse biological activities, particularly antimicrobial and anticancer potential. In the present study, a series of new hybrid compounds consisting of 2-mercaptobenzothiazole and different aryl amines 2(a–j)… read more here.
Keywords: potential novel; antibacterial potential; activity; acetamide derivatives ... See more keywords
A potential and novel type transgenic corn plant for control of the Corn Borer
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44105
Abstract: The corn borer is a world-wide agricultural pest. In this study, a full-length neuropeptide F (npf) gene in Ostrinia furnacalis was sequenced and cloned from a cDNA library, in which the npf gene produces two… read more here.
Keywords: potential novel; corn; control; corn borer ... See more keywords
A potential novel inflammation biomarker for predicting the prognosis of decompensated liver cirrhosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2142277
Abstract: Abstract Objective This study aimed to explore the prognostic value of the lymphocyte (LYM)-to-white blood cell (WBC) ratio (LWR) in patients with decompensated liver cirrhosis (DLC). Methods This study was conducted by recruiting 214 patients… read more here.
Keywords: potential novel; liver cirrhosis; decompensated liver; cohort ... See more keywords
Potential of novel food-borne Lactobacillus isolates against the honeybee pathogen Paenibacillus larvae
Sign Up to like & getrecommendations! Published in 2020 at "Biocontrol Science and Technology"
DOI: 10.1080/09583157.2020.1769556
Abstract: ABSTRACT An in vitro study was conducted to screen for the inhibitory potential of lactic acid bacteria (LAB), isolated from fermented food matrices, against the honeybee American Foulbrood agent Paenibacillus larvae. Various strains of Lactobacillus… read more here.
Keywords: potential novel; borne lactobacillus; food; food borne ... See more keywords
Potential Novel RNA-Targeting Agents for Effective Lipoprotein(a) Lowering: A Systematic Assessment of the Evidence from Completed and Ongoing Developmental Clinical Trials.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001429
Abstract: ABSTRACT An increase in blood lipoprotein (a) [Lp(a)] levels, mostly genetically determined, has been identified as an independent risk factor for atherosclerotic cardiovascular disease. No drug has yet been approved that markedly lowers Lp(a) and… read more here.
Keywords: potential novel; rna targeting; clinical trials; lipoprotein ... See more keywords
Abstract 1107: LAG3 in Solid Tumors as a Potential Novel Immunotherapy Target
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1107
Abstract: We performed prospective immunohistochemical analysis of LAG3 for 430 consecutive patients with advanced gastrointestinal, genitourinary, or rare cancers between June 2012 and March 2016. Most patients (428/430, 99.5%) were evaluable for LAG3 expression by immunohistochemistry.… read more here.
Keywords: tumors potential; novel immunotherapy; potential novel; target ... See more keywords
Abstract 2966: Exploring the therapeutic potential of a novel Siglec-6 targeted bispecific antibody to selectively kill leukemia cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2966
Abstract: Objectives of the Study: Bispecific antibodies (BsAbs) are a class of immunotherapy drugs that facilitate targeted killing of cancer cells. Here, we report therapeutic potential of a novel Siglec-6/CD3 targeted bsAb against chronic lymphocytic leukemia… read more here.
Keywords: potential novel; therapeutic potential; leukemia; siglec targeted ... See more keywords