Potential roles of NLRP3 inflammasome in the pathogenesis of Kawasaki disease
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30948
Abstract: There is a heterogeneous group of rare illnesses that fall into the vasculitis category and are characterized mostly by blood vessel inflammation. Ischemia and disrupted blood flow will cause harm to the organs whose blood… read more here.
Keywords: kawasaki disease; etiology; pathogenesis; potential roles ... See more keywords
Potential roles of heparanase in cancer therapy: Current trends and future direction
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30995
Abstract: Heparanase (HPSE; heparanase‐1) is an endo‐β‐glucuronidase capable of degrading the carbohydrate moiety of heparan sulfate proteoglycans, thus modulating and facilitating the remodeling of the extracellular matrix and basement membrane. HPSE activity is strongly associated with… read more here.
Keywords: hpse; potential roles; heparanase; roles heparanase ... See more keywords
Potential roles of nuclear receptors in mediating neurodevelopmental toxicity of known endocrine‐disrupting chemicals in ascidian embryos
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23219
Abstract: Endocrine Disrupting Chemicals (EDCs) are molecules able to interfere with the vertebrate hormonal system in different ways, a major one being the modification of the activity of nuclear receptors (NRs). Several NRs are expressed in… read more here.
Keywords: nuclear receptors; endocrine disrupting; potential roles; roles nuclear ... See more keywords
Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-73234-9_31
Abstract: MicroRNAs (miRNAs) are endogenous short noncoding RNAs with approximately 22 nucleotides. The primary function of miRNAs is the negative regulation of target gene expression via mRNA degradation or translation inhibition. During recent years, much attention… read more here.
Keywords: effects melatonin; antitumor protective; roles micrornas; potential roles ... See more keywords
Potential roles of neutrophils in maintaining the health and productivity of dairy cows during various physiological and physiopathological conditions: a review
Sign Up to like & getrecommendations! Published in 2019 at "Immunologic Research"
DOI: 10.1007/s12026-019-9064-5
Abstract: Neutrophils represent the first line of innate immunity and are the most prominent line of cellular defence against invading microorganisms. On stimulation, they can quickly move through the walls of veins and into the tissues… read more here.
Keywords: physiopathological conditions; roles neutrophils; physiological physiopathological; neutrophils maintaining ... See more keywords
Hepatocellular carcinoma: Mouse models and the potential roles of proteases.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2016.03.047
Abstract: Primary liver cancer is the second most common cause of mortality from cancer. The most common models of hepatocellular carcinoma, which use a chemical and/or metabolic insult, xenograft, or genetic manipulation, are discussed in this… read more here.
Keywords: hepatocellular carcinoma; mouse models; carcinoma; carcinoma mouse ... See more keywords
Potential roles of the IL-6 family in conjunctival fibrosis.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108708
Abstract: Elevated intraocular pressure (IOP) is a significant risk factor for vision loss due to glaucoma, which is a major cause of blindness worldwide. Glaucoma filtration surgery (GFS) is an important method to reduce IOP by… read more here.
Keywords: conjunctival fibrosis; family conjunctival; roles family; gfs ... See more keywords
Identification of transfer RNA-derived fragments and their potential roles in aortic dissection.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.06.039
Abstract: Emerging evidence suggests that majority of the transfer RNA (tRNA)-derived small RNA, including tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs), play a significant role in the molecular mechanisms underlying some human diseases. However, expression of… read more here.
Keywords: roles aortic; trfs tirnas; aortic dissection; transfer rna ... See more keywords
Lateral Habenula and Its Potential Roles in Pain and Related Behaviors.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00067
Abstract: The lateral habenula (LHb) is a tiny structure that acts as a hub, relaying signals from the limbic forebrain structures and basal ganglia to the brainstem modulatory area. Facilitated by updated knowledge and more precise… read more here.
Keywords: lateral habenula; roles pain; habenula potential; related behaviors ... See more keywords
The functions and potential roles of extracellular vesicle noncoding RNAs in gynecological malignancies
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00645-3
Abstract: Extracellular vesicles (EVs) are small membranous vesicles secreted by multiple kinds of cells and are widely present in human body fluids. EVs containing various constituents can transfer functional molecules from donor cells to recipient cells,… read more here.
Keywords: extracellular vesicle; gynecological malignancies; functions potential; noncoding rnas ... See more keywords
Extracellular vesicle-shuttled miRNAs as a diagnostic and prognostic biomarker and their potential roles in gallbladder cancer patients
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-91804-0
Abstract: Circulating microRNAs (miRNAs) in serum extracellular vesicles (EVs) are a promising biomarker in cancer. We aimed to elucidate the serum EVs miRNA biomarkers to identify patients with gallbladder cancer (GBC) and to clarify their potential… read more here.
Keywords: serum evs; diagnostic prognostic; mir 1246; potential roles ... See more keywords