Adamantinomatous craniopharyngioma in the molecular age and the potential of targeted therapies: a review
Sign Up to like & getrecommendations! Published in 2020 at "Child's Nervous System"
DOI: 10.1007/s00381-020-04677-5
Abstract: Pediatric adamantinomatous craniopharyngiomas (ACPs) are histologically benign brain tumors that often follow an aggressive clinical course. Arising in the sellar/suprasellar region, they grow in close proximity to critical neurological and vascular structures and can result… read more here.
Keywords: adamantinomatous craniopharyngioma; craniopharyngioma molecular; age potential; molecular age ... See more keywords
Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies.
Sign Up to like & getrecommendations! Published in 2020 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.0c00075
Abstract: Engineered nanoparticles (NPs) to specifically deliver payload therapeutics to target cells involved in pathophysiological processes seem to offer a powerful strategy to overcome intrinsic limitations of drugs. In this Viewpoint we disclose the synergistic potential… read more here.
Keywords: targeted nanoparticles; perspective nanotherapies; chemistry; potential targeted ... See more keywords
The Woman's Heart: Insights into New Potential Targeted Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666161118121647
Abstract: Cardiovascular disease is an increasingly common cause of death in women. There is as yet no consensus on the analysis of cardiovascular risk factors with regard to the specific, personalised treatment of pre- and post-menopausal… read more here.
Keywords: heart; heart insights; new potential; potential targeted ... See more keywords
Macrophage, a potential targeted therapeutic immune cell for cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.908790
Abstract: Cardiomyopathy is a major cause of heart failure, leading to systolic and diastolic dysfunction and promoting adverse cardiac remodeling. Macrophages, as key immune cells of the heart, play a crucial role in inflammation and fibrosis.… read more here.
Keywords: potential targeted; immune cell; therapeutic immune; macrophage potential ... See more keywords
Potential Targeted Therapies in Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15111324
Abstract: Background: We aimed to identify somatic pathogenic and likely pathogenic mutations using next-generation sequencing (NGS). The mutational findings were held against clinically well-described data to identify potential targeted therapies in Danish patients diagnosed with high-grade… read more here.
Keywords: potential targeted; targeted therapies; ovarian cancer; platinum sensitive ... See more keywords
Dianthin and Its Potential in Targeted Tumor Therapies
Sign Up to like & getrecommendations! Published in 2019 at "Toxins"
DOI: 10.3390/toxins11100592
Abstract: Dianthin enzymes belong to ribosome-inactivating proteins (RIPs) of type 1, i.e., they only consist of a catalytic domain and do not have a cell binding moiety. Dianthin-30 is very similar to saporin-S3 and saporin-S6, two… read more here.
Keywords: targeted tumor; tumor therapies; potential targeted; dianthin potential ... See more keywords