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Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz413.069
Abstract: Abstract Background Intrahepatic cholangiocarcinoma (iCCA) is a liver neoplasm with few treatment options and a dismal prognosis. To date, the only curative option remains the surgery. New insights concerning its molecular pathogenesis and genetic heterogeneity…
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Keywords:
mutations intrahepatic;
actionable mutations;
intrahepatic cholangiocarcinoma;
oncology ... See more keywords
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Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2019-037
Abstract: Fusions or truncations of MAP3K8 occur in 33% of spitzoid melanomas and 1.5% of adult melanomas.
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Keywords:
spitzoid melanoma;
actionable map3k8;
potentially actionable;
alterations common ... See more keywords
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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.665484
Abstract: Background Several oncogenic drivers in non-small cell lung cancer (NSCLC) are considered actionable with available or promising targeted therapies. Although targetable drivers rarely overlap with each other, there were a minority of patients harboring co-occurring…
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Keywords:
drivers non;
actionable oncogenic;
oncogenic drivers;
occurring potentially ... See more keywords
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Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1086908
Abstract: Background Sarcomatoid hepatocellular carcinoma (SHC) is a rare epithelial malignancy with high invasiveness and poor prognosis. However, the molecular characteristics and main driver genes for SHC have not been determined. The aim of this study…
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Keywords:
hepatocellular carcinoma;
prognosis;
potentially actionable;
sarcomatoid hepatocellular ... See more keywords