Structure–activity investigation of the potentiating effect of cyano substitution on nitroaniline mutagenicity in the ames test
Sign Up to like & getrecommendations! Published in 2018 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22161
Abstract: 2,6‐Dicyano‐4‐nitroaniline and 2‐cyano‐4‐nitroaniline (CNNA; 2‐amino‐5‐nitrobenzonitrile) are potent mutagens in the Ames test, even though unsubstituted nitroanilines (NAs) are no more than weak mutagens. These compounds are putative reduction products of many commercial azo dyes, including… read more here.
Keywords: potentiating effect; effect cyano; disperse; cyano ... See more keywords
The potentiating effect of hTFPI in the presence of hCD47 reduces the cytotoxicity of human macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Xenotransplantation"
DOI: 10.1111/xen.12301
Abstract: In pig‐to‐human xenotransplantation, hyperacute rejection of pig organs could be overcome by the production of α1,3‐galactosyltransferase knockout pigs. However, macrophage‐mediated acute rejection is another obstacle that needs to be overcome. Among the various candidate genes… read more here.
Keywords: hcd47 reduces; reduces cytotoxicity; potentiating effect; effect htfpi ... See more keywords