Tofacitinib for the treatment of chronic pouchitis: A pilot study
Sign Up to like & getrecommendations! Published in 2025 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12683
Abstract: Abstract Background & Aims Up to 15% of ulcerative colitis (UC) patients with an ileo‐anal pouch will develop chronic or antibiotic refractory pouchitis. We aimed to evaluate the efficacy and safety of tofacitinib in these… read more here.
Keywords: treatment; pouchitis; pilot study; chronic pouchitis ... See more keywords
Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-017-2906-5
Abstract: IntroductionUlcerative colitis (UC) is a common, chronic, inflammatory process limited to the colon. UC affects up to 1 million individuals in the USA alone and requires resection in up to 30% of patients. Resection is… read more here.
Keywords: refractory; retrospective review; pouchitis; green tea ... See more keywords
Effective use of ustekinumab for prepouch ileitis without improvement of concomitant pouchitis
Sign Up to like & getrecommendations! Published in 2018 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-018-1754-9
Abstract: Dear Sir, About one half of all patients with ulcerative colitis who have had a restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) experience at least one flare of pouchitis within the first 10 years after… read more here.
Keywords: pouchitis; afferent limb; prepouch ileitis; patient ... See more keywords
Prediction of pouchitis after ileal pouch–anal anastomosis in patients with ulcerative colitis using artificial intelligence and deep learning
Sign Up to like & getrecommendations! Published in 2022 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-022-02602-3
Abstract: Pouchitis is one of the major postoperative complications of ulcerative colitis (UC), and it is still difficult to predict the development of pouchitis after ileal pouch–anal anastomosis (IPAA) in UC patients. In this study, we… read more here.
Keywords: ileostomy closure; prediction; pouchitis; model ... See more keywords
Placebo Rates in Randomized Controlled Trials of Pouchitis Therapy
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DOI: 10.1007/s10620-018-5199-9
Abstract: BackgroundApproximately half of the patients with ulcerative colitis (UC) who undergo restorative proctocolectomy develop pouchitis within 10 years of surgery. Currently, there are no approved pouchitis treatments. It is important to quantify, and ultimately minimize, placebo… read more here.
Keywords: pouchitis; randomized controlled; response; controlled trials ... See more keywords
Clinical Discrimination of Chronic Pouchitis After Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04842-w
Abstract: We aimed to identify predictive factors for the development of chronic pouchitis after ileal pouch-anal anastomosis in patients with ulcerative colitis. Three hundred eighty-seven patients who underwent ileal pouch-anal anastomosis for diagnosis of ulcerative colitis… read more here.
Keywords: pouchitis; pouchitis patients; ileal pouch; ulcerative colitis ... See more keywords
Colectomy risk score predicts pouchitis in patients with ulcerative colitis
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DOI: 10.1007/s13304-021-01166-5
Abstract: Risk stratification is required to improve the management of pouchitis with ulcerative colitis (UC) patients who undergo ileal pouch-anal anastomosis (IPAA). Recently, the colectomy risk score (CRS) has been used to assess UC severity and… read more here.
Keywords: pouchitis; risk; pouchitis patients; crs ... See more keywords
Ileal Pouch Anal Anastomosis (IPAA) for colitis; development of Crohn's and Pouchitis.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2022.01.018
Abstract: BACKGROUND Chronic pouchitis and Crohn's disease after Ileal pouch anal anastomosis (IPAA) for ulcerative colitis could be a larger issue than previously reported. METHODS All patients receiving care for their IPAA over a 10-year period… read more here.
Keywords: ipaa; colitis; pouchitis; crohn ... See more keywords
Reliability among central readers in the evaluation of endoscopic disease activity in pouchitis.
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DOI: 10.1016/j.gie.2018.04.2330
Abstract: BACKGROUND AND AIMS Pouchitis is a common adverse event after proctocolectomy with ileal pouch anal anastomosis for ulcerative colitis. Evaluation of pouchitis disease activity and response to treatment requires use of validated indices. We assessed… read more here.
Keywords: reliability; disease activity; endoscopic; pouchitis ... See more keywords
Single Cell Transcriptional Survey of Ileal-Anal Pouch Immune Cells from Ulcerative Colitis Patients.
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology"
DOI: 10.1053/j.gastro.2020.12.030
Abstract: BACKGROUND & AIMS Restorative proctocolectomy with ileal pouch-anal anastomosis is a surgical procedure in patients with ulcerative colitis refractory to medical therapies. Pouchitis, the most common complication, is inflammation of the pouch of unknown etiology.… read more here.
Keywords: single cell; immune; pouchitis; colitis ... See more keywords
Identification of gut microbiome and transcriptome changes in ulcerative colitis and pouchitis
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DOI: 10.1080/00365521.2022.2047221
Abstract: Abstract Background Pouchitis is the common postoperative complication of ulcerative colitis (UC) and is also considered as inflammatory bowel disease. The aim was to investigate the microbiological and transcriptional differences between the two illnesses. Methods… read more here.
Keywords: microbiome transcriptome; ulcerative colitis; pouchitis; identification gut ... See more keywords