Step-Controlled Povarov-Type Reaction with 1,2-Dihydroquinolines as Precursors of Dienophiles: Direct Synthesis of Spirocyclic Bi-tetrahydroquinolines and Functionalized 1,2-Dihydroquinolines.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.6b03330
Abstract: A novel Povarov-type reaction for straightforward synthesis of novel spiro bi-tetrahydroquinolines with readily available 1,2-DHQs (1,2-dihydroquinolines) and aromatic imines was developed. The reaction could be selectively stopped at the first stage under a Brønsted acid… read more here.
Keywords: povarov type; controlled povarov; reaction; type reaction ... See more keywords
A povarov-type reaction to access tetrahydroquinolines from N-benzylhydroxylamines and alkenes in HFIP.
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DOI: 10.1039/d4cc04014g
Abstract: Here, we report the synthesis of tetrahydroquinolines between newly developed N-benzylhydroxylamine reagents and alkenes using HFIP as a solvent. This transformation is notably applicable to highly electronically deactivated styrenes and aliphatic alkenes, expanding the range… read more here.
Keywords: povarov type; reaction access; tetrahydroquinolines benzylhydroxylamines; access tetrahydroquinolines ... See more keywords
Achievements in the Photocatalytic Povarov–Type Reactions: a Key Step in Green Diversifying the Chemical Quinoline Space
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DOI: 10.1039/d5qo00099h
Abstract: The advances in the Povarov reactions under visible-light conditions, leading to the generation of diverse bioactive quinoline molecules, were thoroughly described and analysed. Based on the structural classification of Povarov... read more here.
Keywords: type reactions; povarov type; povarov; achievements photocatalytic ... See more keywords