Articles with "powder inhalation" as a keyword



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Fragmented particles containing octreotide acetate prepared by spray drying technique for dry powder inhalation

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Published in 2018 at "Drug Delivery and Translational Research"

DOI: 10.1007/s13346-018-0515-7

Abstract: Dry powder inhalers (DPIs) have been proposed as an alternative administration route for protein and peptide drugs. However, DPI particles are easy to aggregate due to the strong interactions between the particles, leading to poor… read more here.

Keywords: powder inhalation; dry powder; fragmented particles; spray drying ... See more keywords
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Development of fine solid-crystal suspension with enhanced solubility, stability, and aerosolization performance for dry powder inhalation.

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Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.09.024

Abstract: Dry powder for inhalation (DPI) is an attractive approach for the treatment of local lung diseases. However, the application of drugs with poor water solubility is often limited due to the dissolution obstacles in the… read more here.

Keywords: powder inhalation; dry powder; solubility; fine solid ... See more keywords
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Physicochemical stability and aerosolization performance of dry powder inhalation system containing ciprofloxacin hydrochloride

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Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2017.09.019

Abstract: Graphical abstract Figure. No Caption available. HighlightsThe role of polyvinyl alcohol, l‐leucine and Hydroxypropyl‐beta‐cyclodextrin on physico‐chemical stability and aerolization performance of dry powder inhalation systems was investigated.Laser diffraction, SEM, DSC, XRPD and in vitro aerodynamical… read more here.

Keywords: powder inhalation; dry powder; system; powder ... See more keywords
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Preparation and Quality Evaluation of Salvianolic Acids and Tanshinones Dry Powder Inhalation.

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Published in 2018 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2018.05.018

Abstract: Salvianolic acids and tanshinones both exhibit efficacy in treating idiopathic pulmonary fibrosis (IPF), but their formulation limits their clinical use. This study aimed to prepare the salvianolic acids and tanshinones dry powder for inhalation (SPI)… read more here.

Keywords: powder inhalation; dry powder; tanshinones dry; acids tanshinones ... See more keywords
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Dry powder inhalation, part 1: ancient history and precursors to modern dry powder inhalers

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Published in 2022 at "Expert Opinion on Drug Delivery"

DOI: 10.1080/17425247.2022.2112568

Abstract: ABSTRACT Introduction Inhalation of herbs and other compounds has a long history but habits for medical treatment are intertwined with rituals to obtain hallucinatory effects and pleasurable sensations. Several examples of inhaled herbs, and the… read more here.

Keywords: history; powder inhalers; dry powder; powder inhalation ... See more keywords
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Pulmonary Targeting of Levofloxacin Using Microsphere-Based Dry Powder Inhalation

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Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15050560

Abstract: The objective of the current study was to develop poly (lactic-co-glycolic acid) (PLGA) microspheres loaded with the anti-tuberculosis (anti-TB) fluoroquinolone, Levofloxacin (LVX), in the form of dry powder inhalation (DPI). LVX-loaded microspheres were fabricated by… read more here.

Keywords: lvx loaded; loaded microspheres; dry powder; powder inhalation ... See more keywords
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Development of High Dose Oseltamivir Phosphate Dry Powder for Inhalation Therapy in Viral Pneumonia

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Published in 2020 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics12121154

Abstract: Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of influenza and as a potential treatment option when in combination with other medication in the fight against the corona… read more here.

Keywords: powder inhalation; dry powder; drug; oseltamivir phosphate ... See more keywords
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Systemic Delivery of hGhrelin Derivative by Lyophilizate for Dry Powder Inhalation System in Monkeys

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13020233

Abstract: Ghrelin is the peptide that increases the hunger sensation and food intake and is expected to be clinically applied for treatment of diseases such as cachexia and anorexia nervosa. In the clinical application of ghrelin,… read more here.

Keywords: hghrelin; powder inhalation; dry powder; lyophilizate dry ... See more keywords