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Published in 2018 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-018-0515-7
Abstract: Dry powder inhalers (DPIs) have been proposed as an alternative administration route for protein and peptide drugs. However, DPI particles are easy to aggregate due to the strong interactions between the particles, leading to poor…
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Keywords:
powder inhalation;
dry powder;
fragmented particles;
spray drying ... See more keywords
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Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.09.024
Abstract: Dry powder for inhalation (DPI) is an attractive approach for the treatment of local lung diseases. However, the application of drugs with poor water solubility is often limited due to the dissolution obstacles in the…
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Keywords:
powder inhalation;
dry powder;
solubility;
fine solid ... See more keywords
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Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.09.019
Abstract: Graphical abstract Figure. No Caption available. HighlightsThe role of polyvinyl alcohol, l‐leucine and Hydroxypropyl‐beta‐cyclodextrin on physico‐chemical stability and aerolization performance of dry powder inhalation systems was investigated.Laser diffraction, SEM, DSC, XRPD and in vitro aerodynamical…
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Keywords:
powder inhalation;
dry powder;
system;
powder ... See more keywords
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Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2018.05.018
Abstract: Salvianolic acids and tanshinones both exhibit efficacy in treating idiopathic pulmonary fibrosis (IPF), but their formulation limits their clinical use. This study aimed to prepare the salvianolic acids and tanshinones dry powder for inhalation (SPI)…
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Keywords:
powder inhalation;
dry powder;
tanshinones dry;
acids tanshinones ... See more keywords
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Published in 2022 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2022.2112568
Abstract: ABSTRACT Introduction Inhalation of herbs and other compounds has a long history but habits for medical treatment are intertwined with rituals to obtain hallucinatory effects and pleasurable sensations. Several examples of inhaled herbs, and the…
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Keywords:
history;
powder inhalers;
dry powder;
powder inhalation ... See more keywords
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Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15050560
Abstract: The objective of the current study was to develop poly (lactic-co-glycolic acid) (PLGA) microspheres loaded with the anti-tuberculosis (anti-TB) fluoroquinolone, Levofloxacin (LVX), in the form of dry powder inhalation (DPI). LVX-loaded microspheres were fabricated by…
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Keywords:
lvx loaded;
loaded microspheres;
dry powder;
powder inhalation ... See more keywords
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Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12121154
Abstract: Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of influenza and as a potential treatment option when in combination with other medication in the fight against the corona…
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Keywords:
powder inhalation;
dry powder;
drug;
oseltamivir phosphate ... See more keywords
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Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13020233
Abstract: Ghrelin is the peptide that increases the hunger sensation and food intake and is expected to be clinically applied for treatment of diseases such as cachexia and anorexia nervosa. In the clinical application of ghrelin,…
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Keywords:
hghrelin;
powder inhalation;
dry powder;
lyophilizate dry ... See more keywords