Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp.
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DOI: 10.1073/pnas.2213771120
Abstract: Bacteria produce a variety of nucleotide second messengers to adapt to their surroundings. Although chemically similar, the nucleotides guanosine penta- and tetraphosphate [(p)ppGpp] and adenosine penta- and tetraphosphate [(p)ppApp] have distinct functions in bacteria. (p)ppGpp… read more here.
Keywords: hydrolyze ppapp; family; identification broadly; ppapp hydrolases ... See more keywords