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Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12858
Abstract: Notch signaling and nuclear receptor PPARγ are involved in macrophage polarization, but cross talk between them has not been reported in macrophages. In this study, the effect of Notch signaling on PPARγ in IL‐4‐stimulated human…
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Keywords:
ppar;
akt;
ppar protein;
protein stability ... See more keywords
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1
Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.21956
Abstract: Diabetic nephropathy (DN) is a common complication of diabetes and it is urgent to develop effective therapies for DN. In this study, high‐sucrose and high‐fat diet combined with streptozotocin was used to induce DN in…
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Keywords:
inflammation;
ppar;
ombuin ameliorates;
ameliorates diabetic ... See more keywords
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1
Published in 2020 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3392
Abstract: We evaluate whether the Pro12Ala polymorphism of peroxisome proliferator‐activated receptor γ2 (PPARγ2) has a role in the progression of diabetes by modulating the occurrence of treatment failure to glucose‐lowering drugs.
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Keywords:
ppar;
failure;
lowering drugs;
pro12ala polymorphism ... See more keywords
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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23041
Abstract: Doxorubicin (Dox) is an antitumor agent widely used in cancer therapy, with notable side effects of cardiac toxicity. Peroxisome proliferator‐activated receptor γ (PPARγ), is a transcriptional factor with antiapoptotic and anti‐inflammatory properties. Recently we indicated…
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Keywords:
ppar;
mir 130a;
dox;
dox induced ... See more keywords
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28190
Abstract: Fatty acid binding protein 4 (FABP4) is a novel tumor regulator that is abnormally expressed in many human cancers. In our study, upregulated microRNA‐211 (miR‐211) and reduced FABP4 expression were detected in colorectal cancer (CRC)…
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Keywords:
ppar;
mir 211;
mir;
colorectal cancer ... See more keywords
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1
Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12352
Abstract: BACKGROUND The present study aimed to uncover the potential effects of zingerone (ZIN), one of the bioactive compounds in ginger, on the development of obesity as well as the mechanisms in C57BL/6J mice fed with…
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Keywords:
adipose tissue;
ppar;
fed mice;
gut microbiota ... See more keywords
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Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23033
Abstract: Considerable progress has been made during the past 20 years towards elucidating the role of peroxisome proliferator‐activated receptor‐β/δ (PPARβ/δ) in skin cancer. In 1999, the original notion that PPARβ/δ was involved with epithelial cell function…
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Keywords:
ppar;
peroxisome proliferator;
proliferator activated;
skin cancer ... See more keywords
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2
Published in 2023 at "Medicinal research reviews"
DOI: 10.1002/med.21970
Abstract: The prevalence of cardiovascular disease (CVD) has been rising due to sedentary lifestyles and unhealthy dietary patterns. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor regulating multiple biological processes, such as lipid metabolism and…
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Keywords:
inflammation;
peroxisome proliferator;
ppar;
proliferator activated ... See more keywords
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Published in 2021 at "Molecular genetics & genomic medicine"
DOI: 10.1002/mgg3.1818
Abstract: BACKGROUND In the new era of tailored cancer treatment strategies, finding a molecule to regulate a wide range of intracellular functions is valuable. The unique property of nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ; PPARG) in…
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Keywords:
ppar;
stimulation using;
ppar stimulation;
expression ... See more keywords
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1
Published in 2018 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22987
Abstract: Elevation of scrotal temperature is one of the most important causes of impaired spermatogenesis and male infertility, but the exact mechanism remains controversial. The present study investigated the impact of camel whey protein (CWP) on…
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Keywords:
ppar;
camel whey;
whey protein;
mice ... See more keywords
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Published in 2018 at "Obesity"
DOI: 10.1002/oby.22030
Abstract: Abnormal fat metabolism is a major disorder in adults who were small for gestational age (SGA). Peroxisome prolferator‐activated receptor (PPARγ) participates in adipocyte differentiation and the regulation of lipid metabolism. This study explored the role…
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Keywords:
ppar;
receptor ppar;
catch growth;
activated receptor ... See more keywords