Antidiabetic Effect of a Flavonoid-Rich Extract from Sophora alopecuroides L. in HFD- and STZ- Induced Diabetic Mice through PKC/GLUT4 Pathway and Regulating PPARα and PPARγ expression.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113654
Abstract: HEADINGS ETHNOPHARMACOLOGICAL RELEVANCE Sophora alopecuroides L. is a traditional ethnopharmacological plant, which is widely used in traditional Chinese medicine and Mongolian and Uighur medicine to ameliorate "thirst disease". AIM OF THE STUDY This study aimed… read more here.
Keywords: medicine; ppar ppar; expression; sophora alopecuroides ... See more keywords
Changes in PPARδ expression in a rat model of stress‐induced depression
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12746
Abstract: Depression is a common mental disorder that has been linked to a decrease in the expression of serotonin and/or the serotonin transporter in the brain. Antidepressants that target the monoaminergic system are widely used in… read more here.
Keywords: serotonin transporter; depression; expression; ppar expression ... See more keywords
CRISPR-mediated BMP9 ablation promotes liver steatosis via the down-regulation of PPARα expression
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DOI: 10.1126/sciadv.abc5022
Abstract: Hepatic cytokine BMP9 attenuates fatty liver by regulating the key lipid metabolism factor PPARα. Obesity drives the development of nonalcoholic fatty liver disease (NAFLD) characterized by hepatic steatosis. Several bone morphogenetic proteins (BMPs) except BMP9… read more here.
Keywords: ppar; liver steatosis; mediated bmp9; ppar expression ... See more keywords