The role of various peroxisome proliferator‐activated receptors and their ligands in clinical practice
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DOI: 10.1002/jcp.25804
Abstract: Peroxisome proliferator‐activated receptors (PPARs) are ligand‐activated transcription factors involved in several physiological processes including modulation of cellular differentiation, development, metabolism of carbohydrates, lipids, proteins, and tumorigenesis. The aim of this review is to examine how… read more here.
Keywords: peroxisome proliferator; ppar ligands; proliferator activated; clinical practice ... See more keywords
PPARβ/δ Ligands Regulate Oxidative Status and Inflammatory Response in Inflamed Corpus Luteum—An In Vitro Study
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DOI: 10.3390/ijms24054993
Abstract: Inflammation in the female reproductive system causes serious health problems including infertility. The aim of this study was to determine the in vitro effects of peroxisome proliferator-activated receptor-beta/delta (PPARβ/δ) ligands on the transcriptomic profile of… read more here.
Keywords: oxidative status; corpus luteum; ppar ligands; response ... See more keywords
Development of Heterocyclic PPAR Ligands for Potential Therapeutic Applications
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DOI: 10.3390/pharmaceutics14102139
Abstract: The family of nuclear peroxisome proliferator-activated receptors (PPARα, PPARβ/δ, and PPARγ) is a set of ligand-activated transcription factors that regulate different functions in the body. Whereas activation of PPARα is known to reduce the levels… read more here.
Keywords: ppar; heterocyclic ppar; ppar ligands; development heterocyclic ... See more keywords