Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05586-w
Abstract: Peroxisome Proliferator Activator receptors (PPARs) are intracellular receptors that function as transcription factors, which regulate specific metabolic and inflammatory processes. PPARs are broadly distributed in the body and are also expressed in the central nervous… read more here.
Keywords: ppar; system; pioglitazone; alcohol consumption ... See more keywords
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2018.09.009
Abstract: We have previously found that the transcription factor PPARγ2 contributes to the mechanism of action of the ketogenic diet (KD), an established treatment for pediatric refractory epilepsy. Among the wide-array of genes regulated by PPARγ,… read more here.
Keywords: ppar; factor ppar; transcription factor; ppar mice ... See more keywords
Downregulation of PTEN Promotes Autophagy via Concurrent Reduction in Apoptosis in Cardiac Hypertrophy in PPAR α−/− Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.798639
Abstract: Cardiac hypertrophy is characterized by an increase in the size of the cardiomyocytes which is initially triggered as an adaptive response but ultimately becomes maladaptive with chronic exposure to different hypertrophic stimuli. Prolonged cardiac hypertrophy… read more here.
Keywords: hypertrophy; ppar; apoptosis; cardiac hypertrophy ... See more keywords