Involvement of the L-arginine/Nitric Oxide/Cyclic GMP/KATP Channel Pathway and PPARĪ³ Receptors in the Peripheral Antinociceptive Effect of Carbamazepine.
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DOI: 10.1055/a-0959-5896
Abstract: Carbamazepine has been shown to exert analgesic effects in clinical and experimental pain situation. This study was conducted to evaluate its potential peripheral antinociceptive effects and the possible involvement of L-arginine/NO/cGMP/KATP channel pathway and PPARĪ³… read more here.
Keywords: carbamazepine; katp channel; channel pathway; paw ... See more keywords
Zerumbone Ameliorates Neuropathic Pain Symptoms via Cannabinoid and PPAR Receptors Using In Vivo and In Silico Models
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DOI: 10.3390/molecules26133849
Abstract: Neuropathic pain is a chronic pain condition persisting past the presence of any noxious stimulus or inflammation. Zerumbone, of the Zingiber zerumbet ginger plant, has exhibited anti-allodynic and antihyperalgesic effects in a neuropathic pain animal… read more here.
Keywords: ppar; neuropathic pain; receptor; zerumbone ... See more keywords