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   Articles with "pparg" as a keyword



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Replication of a Gene-Diet Interaction at CD36, NOS3 and PPARG in Response to Omega-3 Fatty Acid Supplements on Blood Lipids: A Double-Blind Randomized Controlled Trial☆

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recommendations! Published in 2018 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2018.04.012

Abstract: Background Modulation of genetic variants on the effect of omega-3 fatty acid supplements on blood lipids is still unclear. Methods In a double-blind randomized controlled trial, 150 patients with type 2 diabetes (T2D) were randomized… read more here.

Keywords: acid supplements; pparg; fatty acid; omega fatty ... See more keywords
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Obestatin ameliorates water retention in chronic heart failure by downregulating renal aquaporin 2 through GPR39, V2R and PPARG signaling.

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recommendations! Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.05.049

Abstract: AIMS Obestatin regulates water metabolism by inhibiting arginine vasopressin (AVP) release and upregulated obestatin has been detected in patients with chronic heart failure (CHF). However, the significance of obestatin in CHF, particularly with regard to… read more here.

Keywords: water retention; v2r; pparg; water ... See more keywords
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Peroxisome proliferator activated receptor gamma in human placenta may mediate the adverse effects of phthalates exposure in pregnancy.

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recommendations! Published in 2018 at "Reproductive toxicology"

DOI: 10.1016/j.reprotox.2017.10.001

Abstract: Peroxisome-proliferator activated receptor gamma (PPARG) in placenta play an important role in pregnancy. Our previous study showed that it mediated the effects of phthalates on placental mRNA expression of estrogen synthetases in rats. To assess… read more here.

Keywords: peroxisome proliferator; pregnancy; pparg; placenta ... See more keywords
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Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells

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recommendations! Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-12332-0

Abstract: The urothelium is an epithelial barrier lining the bladder that protects against infection, fluid exchange and damage from toxins. The nuclear receptor Pparg promotes urothelial differentiation in vitro, and Pparg mutations are associated with bladder… read more here.

Keywords: pparg; bladder; promotes differentiation; differentiation ... See more keywords
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PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-69363-7

Abstract: Type 2 diabetes mellitus (T2DM) is a complex disease caused by the interaction between genetic and environmental factors. A growing number of evidence suggests that the peroxisome proliferator-activated receptor gamma (PPARG) gene plays a major… read more here.

Keywords: t2dm; risk; pparg; meta analysis ... See more keywords
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PPARG Negatively Modulates Six2 in Tumor Formation of Clear Cell Renal Cell Carcinoma.

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recommendations! Published in 2019 at "DNA and cell biology"

DOI: 10.1089/dna.2018.4549

Abstract: Substantial research has revealed that peroxisome proliferator-activated receptor-gamma (PPARG) plays a critical role in glucose homeostasis and lipid metabolism, and recent studies have shown different effects in the progression of different tumors. However, the role… read more here.

Keywords: cell renal; renal cell; ccrcc; pparg ... See more keywords
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Genetic Associations between Gene Polymorphisms on 3p25 and Oral Squamous Cell Carcinoma.

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recommendations! Published in 2023 at "Oral diseases"

DOI: 10.1111/odi.14514

Abstract: OBJECTIVES To evaluate the association of SYN2, PPARG, RAF1, TIMP4 and IQSEC1 polymorphisms in 3p25 with oral squamous cell carcinoma (OSCC) in the Chinese Han population. SUBJECTS AND METHODS Genomic DNA was extracted from 494… read more here.

Keywords: pparg; iqsec1; squamous cell; cell carcinoma ... See more keywords
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Associations of Leptin Receptor and Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms with Polycystic Ovary Syndrome: A Meta-Analysis

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recommendations! Published in 2019 at "Annals of Nutrition and Metabolism"

DOI: 10.1159/000500996

Abstract: Background: Previous studies on associations of leptin receptor (LEPR) and peroxisome proliferator-activated receptor gamma (PPARG) polymorphisms with polycystic ovary syndrome (PCOS) yielded conflicting results. Objectives: In this meta-analysis, we aimed to better analyze the relationship… read more here.

Keywords: pparg; leptin receptor; associations leptin; receptor ... See more keywords
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Beta-Sitosterol Modulates the Migration of Vascular Smooth Muscle Cells via the PPARG/AMPK/mTOR Pathway

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recommendations! Published in 2022 at "Pharmacology"

DOI: 10.1159/000525218

Abstract: Introduction: The increased migration of vascular smooth muscle cells (VSMCs) is an essential pathological factor in the early development of atherosclerosis. Beta-sitosterol (BS), a natural phytosterol abundant in plant seeds, exhibits various bioactivities, including cardioprotective… read more here.

Keywords: pharmacology; pparg; ampk mtor; migration ... See more keywords
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The relationship between IGF2BP2 and PPARG polymorphisms and susceptibility to esophageal squamous-cell carcinomas in the eastern Chinese Han population

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recommendations! Published in 2017 at "OncoTargets and therapy"

DOI: 10.2147/ott.s145776

Abstract: The aim of this case–control study was to assess whether PPARG and IGF2BP2 polymorphisms confer susceptibility to esophageal squamous-cell carcinoma (ESCC). A total of 507 patients pathologically confirmed for ESCC and 1,496 age-, sex-, and… read more here.

Keywords: pparg; chinese han; squamous cell; eastern chinese ... See more keywords
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Relationship of PPARG, PPARGC1A, and PPARGC1B polymorphisms with susceptibility to hepatocellular carcinoma in an eastern Chinese Han population

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recommendations! Published in 2018 at "OncoTargets and therapy"

DOI: 10.2147/ott.s168274

Abstract: Background PPARG, PPARGC1A, and PPARGC1B polymorphisms may be implicated in the development of cancer. Participants and methods In this study, we selected PPARG rs1801282 C>G and rs3856806 C>T, PPARGC1A rs2970847 C>T, and PPARGC1B rs7732671 G>C… read more here.

Keywords: risk; hcc; ppargc1b; pparg ... See more keywords