Association of the Gly482Ser PPARGC1A gene variant with different cholesterol outcomes in response to two energy-restricted diets in subjects with excessive weight.
Sign Up to like & getrecommendations! Published in 2018 at "Nutrition"
DOI: 10.1016/j.nut.2017.10.008
Abstract: OBJECTIVES The aim of this study was to investigate the influence of two PPARGC1A gene polymorphisms on metabolic outcomes in response to two energy-restricted diets. METHODS A 4-mo nutritional intervention was conducted that involved two… read more here.
Keywords: cholesterol; gly482ser; energy restricted; ppargc1a gene ... See more keywords
SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence
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DOI: 10.1080/15548627.2019.1659612
Abstract: ABSTRACT Defective macroautophagy/autophagy and mitochondrial dysfunction are known to stimulate senescence. The mitochondrial regulator PPARGC1A (peroxisome proliferator activated receptor gamma, coactivator 1 alpha) regulates mitochondrial biogenesis, reducing senescence of vascular smooth muscle cells (VSMCs); however,… read more here.
Keywords: senescence; ppargc1a; autophagy; smooth muscle ... See more keywords
Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0284827
Abstract: Objectives Muscle health is essential for children’s physical development and future health. PPARGC1A gene encode the peroxisome proliferator-activated receptor coactivator 1α which coactivates transcription factors that control mediating skeletal muscle fiber type conversion and skeletal… read more here.
Keywords: gly482ser; ppargc1a; gly482ser polymorphism; muscle ... See more keywords
Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2016050508
Abstract: AKI is a frequent condition that involves renal microcirculation impairment, infiltration of inflammatory cells with local production of proinflammatory cytokines, and subsequent epithelial disorders and mitochondrial dysfunction. Peroxisome proliferator-activated receptor γ coactivator 1-α (PPARGC1A), a… read more here.
Keywords: respiration; hepatocyte nuclear; ppargc1a; factor ... See more keywords
PPARGC1A rs3736265 G>A polymorphism is associated with decreased risk of type 2 diabetes mellitus and fasting plasma glucose level
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16307
Abstract: It has been reported that peroxisome proliferator-activated receptor gamma (PPARG) and peroxisome proliferator-activated receptor gamma co-activator 1 (PPARGC1) family (e.g. PPARGC1A and PPARGC1B) are key agents in the development and pathophysiology of type 2 diabetes… read more here.
Keywords: ppargc1a rs3736265; decreased risk; level; rs3736265 polymorphism ... See more keywords
MiR-93-5p Promotes Cell Proliferation through Down-Regulating PPARGC1A in Hepatocellular Carcinoma Cells by Bioinformatics Analysis and Experimental Verification
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.3390/genes9010051
Abstract: Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A, formerly known as PGC-1a) is a transcriptional coactivator and metabolic regulator. Previous studies are mainly focused on the association between PPARGC1A and hepatoma. However, the regulatory mechanism remains… read more here.
Keywords: cell proliferation; analysis; mir; ppargc1a ... See more keywords