Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function.
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DOI: 10.2337/db23-0531
Abstract: Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit… read more here.
Keywords: brown adipocyte; ppargc1b expression; human genetic; expression ... See more keywords