PPDPF Promotes the Development of Mutant KRAS‐Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1
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DOI: 10.1002/advs.202202448
Abstract: The guanine nucleotide exchange factor (GEF) SOS1 catalyzes the exchange of GDP for GTP on RAS. However, regulation of the GEF activity remains elusive. Here, the authors report that PPDPF functions as an important regulator… read more here.
Keywords: sos1; ductal adenocarcinoma; ppdpf; gef activity ... See more keywords