Articles with "ppel like" as a keyword



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Coexpression network analysis identified Krüppel‐like factor 6 (KLF6) association with chemosensitivity in ovarian cancer

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27567

Abstract: Although most patients with ovarian cancer (OC) are initially sensitive to paclitaxel/carboplatin combination chemotherapy, eventually they develop resistance to chemotherapy drugs and experience disease relapse. OC is the most lethal gynecological malignancy, and the five‐year… read more here.

Keywords: network; analysis; ppel like; ovarian cancer ... See more keywords
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Predictive value of transcriptional expression of Krüppel-like factor-6 (KLF6) in head and neck carcinoma patients treated with radiotherapy

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Published in 2021 at "Clinical and Translational Oncology"

DOI: 10.1007/s12094-021-02651-4

Abstract: To analyse the relationship between the transcriptional expression of Krüppel-like factor-6 (KLF6) and local response to treatment with radiotherapy in patients with head and neck squamous cell carcinoma (HNSCC). We determined the transcriptional expression of… read more here.

Keywords: expression ppel; ppel like; expression; local recurrence ... See more keywords
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Backbone 1H, 13C, and 15N NMR resonance assignments of the Krüppel-like factor 4 activation domain

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Published in 2017 at "Biomolecular NMR Assignments"

DOI: 10.1007/s12104-017-9727-x

Abstract: Krüppel-like factor 4 (KLF4) is a transcription factor involved in diverse biological processes, including development, cellular differentiation and proliferation, and maintenance of tissue homeostasis. KLF4 has also been associated with disease states, such as cardiovascular… read more here.

Keywords: ppel like; like factor; activation domain; activation ... See more keywords
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Genome-wide identification, evolution of Krüppel-like factors (klfs) and their expressions during GCRV challenge in grass carp (Ctenopharyngodon idella).

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Published in 2021 at "Developmental and comparative immunology"

DOI: 10.1016/j.dci.2021.104062

Abstract: The Krüppel-like factors (KLFs) are a family of transcription factors containing three highly conserved tandem zinc finger structures, and each member participates in multiple physiological and pathological processes. The publication of genome sequences and the… read more here.

Keywords: grass; grass carp; like factors; ppel like ... See more keywords
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Krüppel like factor 10 prevents intervertebral disc degeneration via TGF-β signaling pathway both in vitro and in vivo

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Published in 2021 at "Journal of Orthopaedic Translation"

DOI: 10.1016/j.jot.2021.04.003

Abstract: Background Krüppel like factor 10 (KLF10), which is also known as TGF-β Inducible Early Gene-1 (TIEG1), plays a crucial role in regulating cell proliferation, cell apoptosis and inflammatory reaction in human carcinoma cells. Moreover, KLF10… read more here.

Keywords: klf10; degeneration; ppel like; signaling pathway ... See more keywords
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Dysregulation of Krüppel-like factor 12 in the development of endometrial cancer.

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Published in 2019 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2018.10.028

Abstract: OBJECTIVE Endometrial cancer (EC) remains a malignancy with poor survival outcome. To investigate the role of Krüppel-like factor 12 (KLF12), a transcription factor, in the progression of human EC. METHODS Immunohistochemistry, real time-PCR and western… read more here.

Keywords: ppel like; endometrial cancer; expression; factor ... See more keywords
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Increased Krüppel-like factor 12 impairs embryo attachment via downregulation of leukemia inhibitory factor in women with recurrent implantation failure

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Published in 2018 at "Cell Death Discovery"

DOI: 10.1038/s41420-018-0088-8

Abstract: Recurrent implantation failure (RIF) caused by various etiological factors remains a challenge for fertility clinicians using assisted reproductive technology (ART) worldwide. Dysregulation of leukemia inhibitory factor (LIF) in the endometria of women with RIF is… read more here.

Keywords: inhibitory factor; ppel like; leukemia inhibitory; factor ... See more keywords
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Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-16758-9

Abstract: The conversion of white adipocytes to thermogenic beige adipocytes represents a potential mechanism to treat obesity and related metabolic disorders. However, the mechanisms involved in converting white to beige adipose tissue remain incompletely understood. Here… read more here.

Keywords: factor klf3; like factor; tissue; ppel like ... See more keywords
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Krüppel-like factors in endothelial cell biology

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Published in 2017 at "Current Opinion in Hematology"

DOI: 10.1097/moh.0000000000000337

Abstract: Purpose of review Krüppel-like factors (KLFs) are a family of transcription factors that regulate integral functions of endothelial cells including inflammation, proliferation, growth, apoptosis, cell differentiation and plasticity, and migration. This review will focus on… read more here.

Keywords: factors endothelial; endothelial cell; like factors; ppel like ... See more keywords
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Loss of Krüppel‐like factor 9 facilitates stemness in ovarian cancer ascites‐derived multicellular spheroids via Notch1/slug signaling

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Published in 2021 at "Cancer Science"

DOI: 10.1111/cas.15100

Abstract: The ascites that develops in advanced OC, both at diagnosis and upon recurrence, is a rich source of multicellular spheroids/aggregates (MCSs/MCAs), which are the major seeds of tumor cell dissemination within the abdominal cavity. However,… read more here.

Keywords: like factor; ppel like; ascites derived; cancer ... See more keywords
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Krüppel-Like Factor 7 is a Marker of Aggressive Gastric Cancer and Poor Prognosis

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Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000481748

Abstract: Background/Aims: Krüppel-like factor (KLF) 7 protein is a member of the KLF transcription factor family, which plays important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation and metabolism. However, the… read more here.

Keywords: like factor; gastric cancer; klf7; ppel like ... See more keywords