Association Between Proton Pump Inhibitor Use and Risk of Fracture in Children.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2020.0007
Abstract: Importance Proton pump inhibitor (PPI) use has been linked to increased risk of fracture in adults. Despite a trend in prescription of PPIs in children, there is scarce evidence regarding this safety concern in pediatric… read more here.
Keywords: risk fracture; ppi use; use; fracture ... See more keywords
Proton Pump Inhibitors and Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B or C
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30247
Abstract: Researchers have hypothesized that the long‐term use of proton pump inhibitors (PPIs) can increase the risk of developing cancer. However, the association between PPI use and hepatocellular carcinoma (HCC) risk is unclear. Using data from… read more here.
Keywords: risk developing; risk; patients chronic; ppi use ... See more keywords
Is there a correlation between hypomagnesemia linked to long-term proton pump inhibitor use and the active agent?
Sign Up to like & getrecommendations! Published in 2021 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-021-01834-x
Abstract: One of the electrolyte disorders considered to be linked to proton pump inhibitors (PPI) use is hypomagnesemia. The aim of this study was to assess the incidence of hypomagnesemia linked to long-term PPI use and… read more here.
Keywords: use; ppi use; correlation; proton pump ... See more keywords
The association between proton pump inhibitors use and clinical outcome of patients receiving immune checkpoint inhibitors therapy.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106972
Abstract: BACKGROUND The gut microbiome can mediate the efficacy of immune checkpoint inhibitors (ICI). Meanwhile, proton pump inhibitors (PPI) can modulate the gut microbiome significantly. However, the impact of PPI use on the clinical outcome of… read more here.
Keywords: use clinical; immune checkpoint; ppi use; ppi ... See more keywords
Proton pump inhibitor use and mortality in patients with cirrhosis: a meta-analysis of cohort studies
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193890
Abstract: Abstract Background: Proton pump inhibitor (PPI) is commonly used in patients with cirrhosis. However, some studies demonstrated that PPI use was associated with adverse outcome in patients with cirrhosis. We aimed to perform a meta-analysis… read more here.
Keywords: cohort studies; ppi use; patients cirrhosis; mortality ... See more keywords
Influence of proton pump inhibitor use on clinical outcomes of patients with inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Medicine"
DOI: 10.1080/07853890.2023.2198775
Abstract: Abstract Objective Proton pump inhibitor (PPI) use has been associated with reduced diversity of the gut microbiome and may lead to worse clinical outcomes in inflammatory bowel disease (IBD). We aimed to evaluate whether PPI… read more here.
Keywords: clinical outcomes; ibd; ibd related; ppi use ... See more keywords
Proton Pump Inhibitor Use Before and After a Diagnosis of Inflammatory Bowel Disease.
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DOI: 10.1093/ibd/izad017
Abstract: BACKGROUND Proton pump inhibitors (PPIs) have an impact on the gut microbiome. We investigated whether increased use of PPIs was associated with a diagnosis of inflammatory bowel disease (IBD). METHODS The University of Manitoba IBD… read more here.
Keywords: diagnosis; disease; inflammatory bowel; ppi use ... See more keywords
Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead023
Abstract: OBJECTIVES Gastroesophageal reflux disease (GERD) occurs frequently in patients with systemic sclerosis (SSc). We investigated whether the presence of GERD and/or the use of anti-acid therapy, specifically proton-pump inhibitors (PPIs), are associated with long-term outcomes,… read more here.
Keywords: systemic sclerosis; ppi use; ssc; gerd ... See more keywords
Proton pump inhibitor use and risk of dementia
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DOI: 10.1097/md.0000000000014422
Abstract: Background: Proton pump inhibitors (PPIs) are an established kind of drugs used to the treatment of most acid-related diseases. Some prospective studies have noticed that PPI use was associated with increased dementia risk. However, the… read more here.
Keywords: use risk; ppi use; risk; risk dementia ... See more keywords
Proton pump inhibitors and hypomagnesemia
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017788
Abstract: Supplemental Digital Content is available in the text Abstract Background: Previous meta-analyses have suggested that there might be an association between the use of proton pump inhibitors (PPIs) and the development of hypomagnesemia, although the… read more here.
Keywords: proton pump; hypomagnesemia; ppi use; observational studies ... See more keywords
Proton Pump Inhibitor-Induced Gut Dysbiosis Increases Mortality Rates for Patients with Clostridioides difficile Infection
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00486-22
Abstract: This article demonstrates that daily PPI use was the only avoidable risk factor for death. With more extended PPI use, the mortality rate was higher in patients with CDI. Decreases in Prevotella copri and Ruminococcus… read more here.
Keywords: clostridioides difficile; ppi use; mortality; patients cdi ... See more keywords