Inhibition of Aggregation in B-Sheet Model Peptide by PPII Helix Capping
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DOI: 10.1016/j.bpj.2016.11.316
Abstract: A 12mer peptide (Beta, SWTVEGNKYTYK-NH2) was designed based on the Trpzip model. Beta can form an aggregate with fibril like morphology imaged by TEM. The secondary structure of the fibril was characterized to be anti-parallel… read more here.
Keywords: aggregation; inhibition aggregation; beta; model ... See more keywords
BERT-PPII: The Polyproline Type II Helix Structure Prediction Model Based on BERT and Multichannel CNN
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DOI: 10.1155/2022/9015123
Abstract: Predicting the polyproline type II (PPII) helix structure is crucial important in many research areas, such as the protein folding mechanisms, the drug targets, and the protein functions. However, many existing PPII helix prediction algorithms… read more here.
Keywords: information; ppii; helix structure; helix ... See more keywords