Impact of proton pump inhibitors (PPIs) on sunitinib (SU) pharmacokinetics (PK) and activity in GIST patients (pts).
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DOI: 10.1200/jco.2018.36.15_suppl.11538
Abstract: 11538Background: PPIs alter the PK of several oral drugs, either through a decrease in absorption due to higher GI tract pH, or the induction of efflux pumps such as ABCB1. The PK of SU is… read more here.
Keywords: pump inhibitors; inhibitors ppis; ppis sunitinib; sunitinib pharmacokinetics ... See more keywords