5-aminolevulinic acid induced protoporphyrin IX (ALA-PpIX) fluorescence guidance in meningioma surgery
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-03079-7
Abstract: Introduction5-aminolevulinic acid induced protoporphyrin IX (5-ALA-PpIX) fluorescence guidance has emerged as a valuable surgical adjunct for resection of intracranial tumors.MethodsHere we present a focused review on 5-ALA-PpIX fluorescence guidance for meningiomas.ResultsWe discuss the clinical studies… read more here.
Keywords: fluorescence guidance; ala ppix; ppix fluorescence; fluorescence ... See more keywords
Skin surface Protoporphyrin IX fluorescence is associated with epidermal but not dermal fluorescence intensities.
Sign Up to like & getrecommendations! Published in 2020 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2020.101681
Abstract: BACKGROUND Photodynamic therapy with Protoporphyrin IX (PpIX) is well-established for keratinocyte dysplasia. PpIX fluorescence can be quantified at the skin surface and within skin layers, but their relation is previously undescribed. The study objective was… read more here.
Keywords: microscopy; skin surface; ppix fluorescence; fluorescence ... See more keywords
Optical Characterization of Neurosurgical Operating Microscopes: Quantitative Fluorescence and Assessment of PpIX Photobleaching
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-30247-6
Abstract: Protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (5-ALA) is increasingly used as a fluorescent marker for fluorescence-guided resection of malignant gliomas. Understanding how the properties of the excitation light source and PpIX fluorescence interact with… read more here.
Keywords: fluorescence; optical characterization; ppix; operating microscopes ... See more keywords
Small molecule kinase inhibitors enhance aminolevulinic acid-mediated protoporphyrin IX fluorescence and PDT response in triple negative breast cancer cell lines
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.26.9.098002
Abstract: Abstract. Significance: We demonstrate that clinically used kinase inhibitors such as lapatinib can be used for enhancing aminolevulinic acid (ALA) for tumor fluorescence imaging and photodynamic therapy (PDT). Aim: ALA is used as a prodrug… read more here.
Keywords: ppix fluorescence; kinase; kinase inhibitors; fluorescence pdt ... See more keywords