Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b
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DOI: 10.1126/scitranslmed.abh3831
Abstract: Inflammation has profound but poorly understood effects on metabolism, especially in the context of obesity and nonalcoholic fatty liver disease (NAFLD). Here, we report that hepatic interferon regulatory factor 3 (IRF3) is a direct transcriptional… read more here.
Keywords: ppp2r1b; glucose homeostasis; irf3; obesity ... See more keywords