Articles with "ppq" as a keyword



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PRRT neuroendocrine tumor response monitored using circulating transcript analysis: the NETest

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Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"

DOI: 10.1007/s00259-019-04601-3

Abstract: Peptide receptor radionuclide therapy (PRRT) is effective for metastatic/inoperable neuroendocrine tumors (NETs). Imaging response assessment is usually efficient subsequent to treatment completion. Blood biomarkers such as PRRT Predictive Quotient (PPQ) and NETest are effective in… read more here.

Keywords: response; ppq; recist; non responders ... See more keywords
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Inhibition effects of novel polyketide compound PPQ‐B against influenza A virus replication by interfering with the cellular EGFR pathway

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Published in 2017 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2017.04.007

Abstract: Abstract Development of anti‐influenza A virus (IAV) drugs with novel targets and low toxicity is critical for preparedness against influenza outbreaks. In the current study, our results indicated that the novel polyketide compound purpurquinone B… read more here.

Keywords: iav; inhibition; ppq; virus replication ... See more keywords
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Validating the Psychometric Characteristics of the Perinatal Posttraumatic Stress Disorder Questionnaire (PPQ) in a Chinese Context

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Published in 2018 at "Archives of Psychiatric Nursing"

DOI: 10.1016/j.apnu.2017.09.016

Abstract: Background: Perinatal posttraumatic stress disorder (PPTSD) is a common stress‐induced mental disorder worldwide. The Perinatal Posttraumatic Stress Disorder Questionnaire (PPQ) is an excellent questionnaire that measures the symptoms of PPTSD, but has not been translated… read more here.

Keywords: stress disorder; posttraumatic stress; ppq; stress ... See more keywords
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Effect of a newly synthesized quinoline-based compound (PPQ-8) on murine schistosomiasis mansoni.

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Published in 2020 at "Journal of helminthology"

DOI: 10.1017/s0022149x2000005x

Abstract: Schistosomiasis represents a public health problem and praziquantel is the only drug used for treatment of all forms of the disease. Thus, the development of new anti-schistosomal agents is of utmost importance to increase the… read more here.

Keywords: schistosomiasis; based compound; quinoline based; ppq ... See more keywords
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Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-04104-z

Abstract: Multidrug resistant Plasmodium falciparum in Southeast Asia endangers regional malaria elimination and threatens to spread to other malaria endemic areas. Understanding mechanisms of piperaquine (PPQ) resistance is crucial for tracking its emergence and spread, and… read more here.

Keywords: plasmepsin iii; copy number; resistance; ppq ... See more keywords
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Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages

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Published in 2022 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1010926

Abstract: The emergence of Plasmodium falciparum parasite resistance to dihydroartemisinin + piperaquine (PPQ) in Southeast Asia threatens plans to increase the global use of this first-line antimalarial combination. High-level PPQ resistance appears to be mediated primarily… read more here.

Keywords: plasmodium falciparum; ppq; physiology; resistance ... See more keywords

Isolation of Mutants With Reduced Susceptibility to Piperaquine From a Mutator of the Rodent Malaria Parasite Plasmodium berghei

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Published in 2021 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2021.672691

Abstract: Elucidation of the mechanisms of drug resistance in malaria parasites is crucial for combatting the emergence and spread of resistant parasites, which can be achieved by tracing resistance-associated mutations and providing useful information for drug… read more here.

Keywords: susceptibility; pbmut ppq; ppq; resistance ... See more keywords