The matrix protein of lyssavirus hijacks autophagosome for efficient egress by recruiting NEDD4 through its PPxY motif
Sign Up to like & getrecommendations! Published in 2024 at "Autophagy"
DOI: 10.1080/15548627.2024.2338575
Abstract: ABSTRACT Lyssaviruses are well-known worldwide and often cause fatal encephalitis. Previous studies have shown that autophagy is beneficial for the replication of rabies virus (RABV), the representative lyssavirus, but the detailed mechanism remains obscure. In… read more here.
Keywords: ppxy motif; matrix protein; lyssavirus; protein ... See more keywords
Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006217
Abstract: Cells employ active measures to restrict infection by pathogens, even prior to responses from the innate and humoral immune defenses. In this context selective autophagy is activated upon pathogen induced membrane rupture to sequester and… read more here.
Keywords: ppxy motif; galectin; control; conserved ppxy ... See more keywords