The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00334
Abstract: The opportunistic pathogen Pseudomonas aeruginosa causes antibiotic resistant, nosocomial infections in immuno-compromised individuals, and is a high priority for antimicrobial development. Key to pathogenicity in P. aeruginosa are biofilm formation and virulence factor production. Both… read more here.
Keywords: interaction; pseudomonas aeruginosa; pqse rhlr; rhlr interaction ... See more keywords
The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02108-21
Abstract: Bacteria use a cell-cell communication process called quorum sensing (QS) to orchestrate collective behaviors. QS relies on the group-wide detection of molecules called autoinducers (AI). ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that causes disease… read more here.
Keywords: virulence; pqse rhlr; interaction; cell ... See more keywords