An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function.
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.06.053
Abstract: BACKGROUND There are few clinically useful circulating biomarkers of lung function and lung disease. We hypothesized that genome-wide association studies (GWAS) of circulating proteins in conjunction with GWAS of pulmonary traits represents a clinically-relevant approach… read more here.
Keywords: integrative genomic; srage; pqtl; lung function ... See more keywords
Investigating potential drug targets for the treatment of glioblastoma: a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2025 at "BMC Cancer"
DOI: 10.1186/s12885-025-13979-3
Abstract: Glioblastoma (GBM), one of the most aggressive brain tumors, has a 5-year survival rate of less than 5%. Current standard therapies, including surgery, radiotherapy, and temozolomide (TMZ) chemotherapy, are limited by drug resistance and the… read more here.
Keywords: pqtl; investigating potential; glioblastoma; drug ... See more keywords