Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling
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DOI: 10.1158/1535-7163.mct-17-0008
Abstract: Oncogenic rearrangements in RET are present in 1%–2% of lung adenocarcinoma patients. Ponatinib is a multi-kinase inhibitor with low-nanomolar potency against the RET kinase domain. Here, we demonstrate that ponatinib exhibits potent antiproliferative activity in… read more here.
Keywords: pr2; ret fusion; inhibition; ret inhibition ... See more keywords
The Anti-Termite Activity of Bacillus licheniformis PR2 against the Subterranean Termite, Reticulitermes speratus kyushuensis Morimoto (Isoptera: Rhinotermitidae)
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DOI: 10.3390/f14051000
Abstract: Subterranean termites of the species Reticulitermes speratus kyushuensis Morimoto (Isoptera: Rhinotermitidae) are notoriously destructive soil-dwelling pests that feed on the cellulosic wood biomass. This leads to tremendous losses of forest trees such as Pinus densiflora… read more here.
Keywords: pr2; licheniformis pr2; speratus kyushuensis; reticulitermes speratus ... See more keywords
Exploration of the Crystal Structure and Thermal and Spectroscopic Properties of Monoclinic Praseodymium Sulfate Pr2(SO4)3
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DOI: 10.3390/molecules27133966
Abstract: Praseodymium sulfate was obtained by the precipitation method and the crystal structure was determined by Rietveld analysis. Pr2(SO4)3 is crystallized in the monoclinic structure, space group C2/c, with cell parameters a = 21.6052 (4), b… read more here.
Keywords: structure; pr2; pr2 so4; praseodymium sulfate ... See more keywords