Shunt Nephritis and Pyogenic Spondylitis With a Positive PR3-ANCA Associated With Chronically Infected Ventriculoatrial Shunt
Sign Up to like & getrecommendations! Published in 2017 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2017.02.013
Abstract: INTRODUCTION S hunt nephritis is a rare complication mostly described in the setting of chronic infection of ventriculoatrial (VA) shunts inserted for the treatment of congenital or acquired hydrocephalus. The diagnosis of shunt nephritis is… read more here.
Keywords: pyogenic spondylitis; shunt nephritis; spondylitis positive; pr3 anca ... See more keywords
Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis. A case-control study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2020.102579
Abstract: OBJECTIVES Anti-neutrophil cytoplasmic autoantibodies [ANCA) are important for diagnosis of ANCA-associated vasculitides (AAV). The timing of antibody development is not well established. To investigate the development of proteinase 3 (PR3)- and myeloperoxidase (MPO)-ANCA, blood samples… read more here.
Keywords: anca; pr3 anca; symptom onset; mpo anca ... See more keywords
Difference in relapse-rate and clinical phenotype by autoantibody-subtype in Japanese patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
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DOI: 10.1080/14397595.2016.1192760
Abstract: Abstract Objective: To correlate the serotype specificity to myeloperoxidase (MPO) and proteinase-3 (PR3) with clinical characteristics in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Methods: Clinical characteristics and outcomes of patients with AAV in our division… read more here.
Keywords: relapse; vasculitis; pr3 anca; anca vasculitis ... See more keywords
Infection is associated with increased risk of MPO- but not PR3-ANCA associated vasculitis.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac163
Abstract: OBJECTIVES To determine whether development of ANCA-associated vasculitis (AAV) shows a relationship to a prior infection and if prior infection affects disease characteristics and outcome. METHODS All incident cases of AAV diagnosed in a defined… read more here.
Keywords: infection; pr3 anca; vasculitis; prior infection ... See more keywords
Acute renal failure in a patient with PR3-ANCA and monoclonal immunoglobulin deposition disease
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DOI: 10.1097/md.0000000000013799
Abstract: Rationale: Acute renal failure developing over a short period of time with evidence of glomerular disease by urine sediment microscopy characterizes the clinical syndrome of rapidly progressive glomerulonephritis (RPGN), of which the most common causes… read more here.
Keywords: renal failure; acute renal; disease; pr3 anca ... See more keywords
SAT0236 RELATIONSHIP BETWEEN RITUXIMAB CONCENTRATION AND AUTOANTIBODY LEVELS IN ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY ASSOCIATED VASCULITIS
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DOI: 10.1136/annrheumdis-2019-eular.7552
Abstract: Background: Rituximab is approved in patients with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). Antibodies to proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) decrease with therapy (1) and may therefore be used as biomarkers. Objectives: To… read more here.
Keywords: rituximab; associated vasculitis; pr3 anca; concentration ... See more keywords
PRTN3 variant correlates with increased autoantigen levels and relapse risk in PR3-ANCA versus MPO-ANCA disease
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DOI: 10.1172/jci.insight.166107
Abstract: A GWAS of patients with anti-neutrophil cytoplasmic antibodies (ANCAs) found an association between proteinase-3 ANCA (PR3-ANCA) and a single nucleotide polymorphism (rs62132293) upstream of PRTN3, encoding PR3. The variant (G allele) was shown to be… read more here.
Keywords: pr3; expression; mpo; prtn3 ... See more keywords
PR3-ANCA and panel diagnostics in pediatric inflammatory bowel disease to distinguish ulcerative colitis from Crohn's disease
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DOI: 10.1371/journal.pone.0208974
Abstract: Background Accurate classification of patients with inflammatory bowel disease into the subtypes ulcerative colitis (UC) and Crohn’s disease (CD) is still a challenge, but important for therapy and prognosis. Objectives To evaluate the diagnostic utility… read more here.
Keywords: disease; ulcerative colitis; pr3 anca; panel ... See more keywords
PR3-ANCA-positive Pulmonary Cryptococcosis
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DOI: 10.2169/internalmedicine.8925-17
Abstract: A 68-year-old man had multiple left pulmonary nodules with serum positivity for proteinase 3 anti-neutrophil cytoplasmic autoantibody (PR3-ANCA) and negativity for cryptococcal antigen (Picture 1). We initially regarded him as having granulomatosis with polyangiitis (GPA).… read more here.
Keywords: anca positive; pulmonary cryptococcosis; positive pulmonary; pr3 anca ... See more keywords
Different Types of ANCA Determine Different Clinical Phenotypes and Outcome in ANCA-Associated Vasculitis (AAV)
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DOI: 10.3389/fmed.2021.783757
Abstract: Aim Accumulating evidence supports the use of antineutrophil cytoplasmic antibody (ANCA) type to classify different clinical entities. We aimed to evaluate whether the presence and type of ANCA determine different diseases, based on clinical phenotypes,… read more here.
Keywords: anca anca; mpo anca; anca; histology ... See more keywords