Identification and phenotyping of circulating autoreactive proteinase 3-specific B cells in patients with PR3-ANCA associated vasculitis and healthy controls.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.08.006
Abstract: OBJECTIVES To develop a method to detect and phenotype circulating proteinase 3 (PR3)-specific B-cells in patients with PR3-ANCA associated vasculitis (AAV). METHODS Recombinant human PR3 (rPR3) was tagged with FITC or biotin, and its binding… read more here.
Keywords: pr3; patients pr3; pr3 specific; specific cells ... See more keywords
SAT0021 ELEVATED NUMBERS OF C-TYPE LECTIN CD161 POSITIVE PR3-SPECIFIC T-CELLS IN GPA
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6771
Abstract: Background: Various alterations of the peripheral T-cell compartment have been reported in granulomatosis with polyangiitis (GPA) such as elevated populations of CD4+CD8+ double-positive and CD4+CD161+ and CD28- single-positive effector memory T-cells (TEM) within the total… read more here.
Keywords: cd161; none declared; cd8; pr3 specific ... See more keywords