Conserved Interaction of Lentiviral Vif Molecules with HIV-1 Gag and Differential Effects of Species-Specific Vif on Virus Production
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DOI: 10.1128/jvi.00064-17
Abstract: ABSTRACT The virion infectivity factor (Vif) open reading frame is conserved among most lentiviruses. Vif molecules contribute to viral replication by inactivating host antiviral factors, the APOBEC3 cytidine deaminases. However, various species of lentiviral Vif… read more here.
Keywords: pr55gag; biv vif; vif; interaction ... See more keywords
TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness
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DOI: 10.3390/ijms24087658
Abstract: The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been reported to determine cell permissivity to HIV-1 fusion and infection acting on tubulin-deacetylase HDAC6. Here,… read more here.
Keywords: viral production; pr55gag; production; hiv viral ... See more keywords