Practical Synthesis of Cap‐4 RNA
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201900590
Abstract: Eukaryotic mRNAs possess 5′ caps that are determinants for their function. A structural characteristic of 5′ caps is methylation, with this feature already present in early eukaryotes such as Trypanosoma. While the common cap‐0 (m7GpppN)… read more here.
Keywords: methylation; cap rna; practical synthesis; synthesis cap ... See more keywords
A Practical Synthesis of Valuable Strained Eight‐Membered‐Ring Derivatives for Click Chemistry
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201800139
Abstract: A convenient and cost-effective synthetic access to cyclooctyne and trans-cyclooctene derivatives is described. A cyclopropanation step using copper powder in lieu of Rh₂(OAc)₄ as catalyst and a symmetric diazomalonate enabled to drastically reduce the overall… read more here.
Keywords: click chemistry; practical synthesis; chemistry; chemistry practical ... See more keywords
Gold-catalyzed intermolecular oxidation of phenylacetylene and allylic sulfides: an efficient and practical synthesis of α-phenylthio ketone
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-018-7238-7
Abstract: An efficient and practical synthesis of α-phenylthio ketone through gold-catalyzed intermolecular oxidation of phenylacetylene and substituted aryl(benzyl) allylic sulfides was developed. The reaction scope is fairly good with substituted aryl(benzyl) allylic sulfides, tolerating various functional… read more here.
Keywords: practical synthesis; phenylthio ketone; allylic sulfides; efficient practical ... See more keywords
A practical synthesis of quinazolinones via intermolecular cyclization between 2-halobenzamides and benzylamines catalyzed by copper(I) immobilized on MCM-41
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.07.003
Abstract: Abstract The heterogeneous tandem N-arylation/oxidative C–H amidation of 2-halobenzamides and benzylamines was achieved in DMSO at 110 or 120 °C by using an MCM-41-immobilized l -proline copper(I) complex [MCM-41- l -Proline-CuBr] as the catalyst and air… read more here.
Keywords: synthesis quinazolinones; copper; via intermolecular; quinazolinones via ... See more keywords
Practical synthesis of phosphonium salts with orthoformates and their application as flame retardants in polycarbonate
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131107
Abstract: Abstract An efficient and practical approach to phosphonium salts has been developed. By the reaction of phosphines and different acid sources with orthoformates in one-step operation, the process allowed rapid access to phosphonium salts with… read more here.
Keywords: salts orthoformates; flame; phosphonium; practical synthesis ... See more keywords
Facile and practical synthesis of π-extended oxepins by benzannulation and intramolecular cyclization
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.12.008
Abstract: Abstract π-Extended oxepins 1 and dimer 8 were synthesized by the benzannulation of the corresponding asymmetric diarylacetylene derivatives and 2-(phenylethynyl)benzaldehyde followed by the Cu-catalyzed intramolecular cyclization. The optical properties of the π-extended oxepins 1 and… read more here.
Keywords: intramolecular cyclization; extended oxepins; benzannulation; facile practical ... See more keywords
Practical synthesis of 16α-bromo-17α-hydroxysteroids via a Raney Ni-catalyzed bromide exchange reaction
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.05.049
Abstract: Abstract D-ring modified glucocorticoids are attractive synthetic targets owing to their broad application in medicinal chemistry. Herein, we reported a practical synthesis of 16α-bromo-17α-hydroxysteroids from easily available 16β-bromo isomers via a Raney Ni-catalyzed bromide exchange… read more here.
Keywords: via raney; reaction; bromo hydroxysteroids; synthesis bromo ... See more keywords
Practical synthesis of phthalascidin and zalypsis antitumor agents
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153498
Abstract: Abstract The first total synthesis of zalypsis and the practical synthesis of phthalascidin (Pt-650) are achieved through the Pictet-Spengler cyclization coupling strategy. The direct iodination of the primary alcohol in trihydroxyl intermediate 26 followed by… read more here.
Keywords: synthesis; zalypsis; synthesis phthalascidin; practical synthesis ... See more keywords
Practical synthesis of enantiopure benzylamines by catalytic hydrogenation or transfer hydrogenation reactions in isopropanol using a Ru-pybox catalyst
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00908a
Abstract: The screening of a family of complexes of the formula [RuCl2(R-pybox)(L)] (R-pybox = Ph-, iPr- or indane-pybox; L = monodentate P, N or C ligand) in the enantioselective hydrogenation of N-aryl imines indicates a strong… read more here.
Keywords: hydrogenation; practical synthesis; transfer hydrogenation; pybox ... See more keywords
A practical synthesis of 1,3-disubstituted cubane derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Communications"
DOI: 10.1039/d3cc02164e
Abstract: A robust multigram-scale synthesis of 1,3-disubstituted cubanes (previously only available on milligram-scale) is reported. The approach exploits a readily available enone intermediate previously used for the synthesis of 1,4-disubstituted cubanes, by introducing a novel Wharton… read more here.
Keywords: synthesis disubstituted; disubstituted cubane; disubstituted cubanes; cubane derivatives ... See more keywords
A practical synthesis of 3,4-diamino-6-azido-1H-pyrazolo[4,3-c]pyridin-5-ium energetic ionic compounds
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00343d
Abstract: Energetic ionic compounds have attracted substantial research interest over the past decade due to their relative low sensitivities than corresponding covalent ones. However, by far, the synthesis of energetic ionic... read more here.
Keywords: energetic ionic; azido pyrazolo; diamino azido; synthesis diamino ... See more keywords