Screening of tumor antigens and immunogenic cell death landscapes of prostate adenocarcinoma for exploration of mRNA vaccine
Sign Up to like & getrecommendations! Published in 2024 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2024.2396086
Abstract: ABSTRACT Background In this study, effective antigens of mRNA vaccine were excavated from the perspective of ICD, and ICD subtypes of PRAD were further distinguished to establish an ICD landscape, thereby determining suitable vaccine recipients.… read more here.
Keywords: mrna vaccine; icd subtypes; icd landscape; vaccine ... See more keywords
Zinc finger C3H1 domain-containing protein (ZFC3H1) evaluates the prognosis and treatment of prostate adenocarcinoma (PRAD): A study based on TCGA data.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1965442
Abstract: The present study was aimed to evaluate the expression profile of Zinc finger C3H1 domain-containing protein (ZFC3H1) using bioinformatic analysis of public datasets from The Cancer Genome Atlas database (TCGA). The results showed that the… read more here.
Keywords: protein; zinc finger; finger c3h1; zfc3h1 ... See more keywords
High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/2922832
Abstract: Purpose To elucidate the clinical and prognostic role of PDZ and LIM domain protein (PDLIM) genes and the association to epithelial-mesenchymal transition (EMT) and immune cell infiltration in patients with prostate cancer (PRAD). Methods The… read more here.
Keywords: prad; cell infiltration; immune cell; expression ... See more keywords
Integrative Multiomics Evaluation of IIDH1 Metabolic Enzyme as a Candidate Oncogene That is Correlated with Poor Prognosis and Immune Infiltration in Prostate Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/9854788
Abstract: Mutations in the isocitrate dehydrogenase gene (IDH1) are involved in the progression of tumors. Although IDH1 has a role in various tumors, its clinical relevance and its expression in response to the immune response have… read more here.
Keywords: infiltration; prad; idh1; expression ... See more keywords
Identification of Enzalutamide-Related Genes for Prognosis and Immunotherapy in Prostate Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Human Mutation"
DOI: 10.1155/humu/9755727
Abstract: Enzalutamide is classified as a novel antiandrogen medication; however, the majority of patients ultimately develop resistance to it. Consequently, conducting an in-depth investigation into potential targets of enzalutamide is essential for addressing the drug resistance… read more here.
Keywords: identification enzalutamide; related genes; prognosis; prostate adenocarcinoma ... See more keywords
Abstract 4104: Development of adoptive T-cell therapies to target heterogeneity of mCRPC
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4104
Abstract: Metastatic castration resistant prostate cancer (mCRPC) remains a significant challenge with limited durable therapeutic responses, and innovative and effective treatment strategies are needed. Advanced mCRPC often comprises a heterogeneous population of prostate adenocarcinoma (PrAd) and… read more here.
Keywords: cell; prad; car; mcrpc ... See more keywords
Prognostic value of LncRNA PSMA3-AS1 in prostate cancer and its potential regulatory mechanism
Sign Up to like & getrecommendations! Published in 2025 at "Hereditas"
DOI: 10.1186/s41065-025-00485-6
Abstract: Prostate adenocarcinoma (PRAD) is asymptomatic in the early stages and most patients are diagnosed at an advanced stage, which leads to a poor prognosis. Therefore, an effective prognostic marker is required to improve PRAD prognosis.… read more here.
Keywords: prostate cancer; psma3 as1; psma3; prad ... See more keywords
Machine learning-based screening of potential diagnostic markers for prostate cancer with immune cell infiltration analysis and experimental validation
Sign Up to like & getrecommendations! Published in 2025 at "Translational Andrology and Urology"
DOI: 10.21037/tau-2025-291
Abstract: Background Prostate adenocarcinoma (PRAD) poses a significant global health burden. Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3C (APOBEC3C) exhibits context-dependent roles in cancer but its function in PRAD remains unclear. This study aims to… read more here.
Keywords: cancer; analysis; validation; cell ... See more keywords
High expression of KNL1 in prostate adenocarcinoma is associated with poor prognosis and immune infiltration
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1100787
Abstract: Prostate adenocarcinoma (PRAD) is a common malignancy with increasing morbidity and mortality. Kinetochore scaffold 1 (KNL1) has been reported to be involved in tumor progression and prognosis in other tumors, but its role in PRAD… read more here.
Keywords: prognosis; prad; immune infiltration; expression ... See more keywords
LTF Regulates the Immune Microenvironment of Prostate Cancer Through JAK/STAT3 Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.692117
Abstract: Background The study of the immune microenvironment in prostate cancer (PRAD) has brought new opportunities for the current traditional treatment regimens. Therefore, our goal is to develop a universal immunodiagnostic marker to improve patient survival.… read more here.
Keywords: cancer; group; immune microenvironment; cell ... See more keywords
Integrated bioinformatics analysis of IFITM1 as a prognostic biomarker and investigation of its immunological role in prostate adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1037535
Abstract: Introduction Prostate adenocarcinoma (PRAD) is a highly aggressive malignancy with high mortality and poor prognosis, and its potential mechanism remains unclear. Our study aimed to identify novel markers for the prognosis of PRAD using bioinformatics… read more here.
Keywords: prognostic biomarker; ifitm1 prognostic; prad; prostate adenocarcinoma ... See more keywords