Articles with "prad" as a keyword



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Zinc finger C3H1 domain-containing protein (ZFC3H1) evaluates the prognosis and treatment of prostate adenocarcinoma (PRAD): A study based on TCGA data.

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Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1965442

Abstract: The present study was aimed to evaluate the expression profile of Zinc finger C3H1 domain-containing protein (ZFC3H1) using bioinformatic analysis of public datasets from The Cancer Genome Atlas database (TCGA). The results showed that the… read more here.

Keywords: protein; zinc finger; finger c3h1; zfc3h1 ... See more keywords
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High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/2922832

Abstract: Purpose To elucidate the clinical and prognostic role of PDZ and LIM domain protein (PDLIM) genes and the association to epithelial-mesenchymal transition (EMT) and immune cell infiltration in patients with prostate cancer (PRAD). Methods The… read more here.

Keywords: prad; cell infiltration; immune cell; expression ... See more keywords
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Integrative Multiomics Evaluation of IIDH1 Metabolic Enzyme as a Candidate Oncogene That is Correlated with Poor Prognosis and Immune Infiltration in Prostate Adenocarcinoma

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/9854788

Abstract: Mutations in the isocitrate dehydrogenase gene (IDH1) are involved in the progression of tumors. Although IDH1 has a role in various tumors, its clinical relevance and its expression in response to the immune response have… read more here.

Keywords: infiltration; prad; idh1; expression ... See more keywords
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Abstract 4104: Development of adoptive T-cell therapies to target heterogeneity of mCRPC

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4104

Abstract: Metastatic castration resistant prostate cancer (mCRPC) remains a significant challenge with limited durable therapeutic responses, and innovative and effective treatment strategies are needed. Advanced mCRPC often comprises a heterogeneous population of prostate adenocarcinoma (PrAd) and… read more here.

Keywords: cell; prad; car; mcrpc ... See more keywords

High expression of KNL1 in prostate adenocarcinoma is associated with poor prognosis and immune infiltration

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Published in 2023 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1100787

Abstract: Prostate adenocarcinoma (PRAD) is a common malignancy with increasing morbidity and mortality. Kinetochore scaffold 1 (KNL1) has been reported to be involved in tumor progression and prognosis in other tumors, but its role in PRAD… read more here.

Keywords: prognosis; prad; immune infiltration; expression ... See more keywords
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LTF Regulates the Immune Microenvironment of Prostate Cancer Through JAK/STAT3 Pathway

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.692117

Abstract: Background The study of the immune microenvironment in prostate cancer (PRAD) has brought new opportunities for the current traditional treatment regimens. Therefore, our goal is to develop a universal immunodiagnostic marker to improve patient survival.… read more here.

Keywords: cancer; group; immune microenvironment; cell ... See more keywords
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Integrated bioinformatics analysis of IFITM1 as a prognostic biomarker and investigation of its immunological role in prostate adenocarcinoma

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1037535

Abstract: Introduction Prostate adenocarcinoma (PRAD) is a highly aggressive malignancy with high mortality and poor prognosis, and its potential mechanism remains unclear. Our study aimed to identify novel markers for the prognosis of PRAD using bioinformatics… read more here.

Keywords: prognostic biomarker; ifitm1 prognostic; prad; prostate adenocarcinoma ... See more keywords
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Computer classification and construction of a novel prognostic signature based on moonlighting genes in prostate cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.982267

Abstract: Advanced prostate cancer (PRAD) patients have poor prognosis and rising morbidity despite the ongoing iteration of molecular therapeutic agents. As newly discovered proteins with several functions, Moonlighting proteins have showed an important role in tumor… read more here.

Keywords: prostate cancer; moonlighting genes; prad; signature ... See more keywords
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Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28031238

Abstract: Prostate adenocarcinoma (PRAD) is the most frequent malignancy, and is the second leading cause of death due to cancer in men. Thus, new prognostic biomarkers and drug targets for PRAD are urgently needed. As we… read more here.

Keywords: prognostic biomarker; immune infiltration; prad; prostate adenocarcinoma ... See more keywords