Pralidoxime-Induced Potentiation of the Pressor Effect of Adrenaline and Hastened Successful Resuscitation by Pralidoxime in a Porcine Cardiac Arrest Model
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-07026-5
Abstract: Purpose Pralidoxime potentiated the pressor effect of adrenaline and facilitated restoration of spontaneous circulation (ROSC) after prolonged cardiac arrest. In this study, we hypothesised that pralidoxime would hasten ROSC in a model with a short… read more here.
Keywords: pressor effect; resuscitation; pralidoxime; adrenaline ... See more keywords
The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.114879
Abstract: In a previous work we showed that the organophosphate pesticide (OP) chlorpyrifos (CPF) reduces the protective chemoreflex and baroreflex responses in rats. However, whether the antidotes atropine (ATR) and pralidoxime (2-PAM) are capable of restoring… read more here.
Keywords: chlorpyrifos; antidotes atropine; cardiorespiratory; pam ... See more keywords
The First Use of Pralidoxime in a Child With Rivastigmine Poisoning
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Emergency Care"
DOI: 10.1097/pec.0000000000001086
Abstract: The aim of this report is to describe the successful use of pralidoxime in a pediatric patient who accidentally ingested 12 mg of rivastigmine and presented to the emergency department with weakness, drowsiness, hyporeactivity to… read more here.
Keywords: use pralidoxime; rivastigmine; rivastigmine poisoning; pralidoxime ... See more keywords
High Dose of Pralidoxime Reverses Paraoxon-Induced Respiratory Toxicity in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Turkish journal of anaesthesiology and reanimation"
DOI: 10.5152/tjar.2018.29660
Abstract: Objective The efficiency of pralidoxime in the treatment of human organophosphates poisoning is still unclear. In a rat model, we showed that pralidoxime induced a complete but concentration-dependent reversal of paraoxon-induced respiratory toxicity. The aim… read more here.
Keywords: paraoxon induced; induced respiratory; toxicity; pralidoxime ... See more keywords