Effect of pH on Iontophoretic Transport of Pramipexole Dihydrochloride across Human Epidermal Membrane.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03001-3
Abstract: PURPOSE Drugs with higher molecular charges generally show higher flux enhancement when electromigration is the main mechanism in transdermal iontophoresis. This study evaluated the effect of decreasing the formulation pH to increase the positive charges… read more here.
Keywords: transport; iontophoresis; effect; iontophoretic transport ... See more keywords
Novel contribution to the simultaneous monitoring of pramipexole dihydrochloride monohydrate and levodopa as co-administered drugs in human plasma utilizing UPLC–MS/MS
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Mass Spectrometry"
DOI: 10.1177/1469066718788800
Abstract: An efficient, selective, sensitive, and rapid ultra-performance liquid chromatography tandem mass spectrometry method was established and validated for the quantification of pramipexole dihydrochloride monohydrate and levodopa simultaneously in human plasma with the aid of diphenhydramine… read more here.
Keywords: plasma; dihydrochloride monohydrate; pramipexole dihydrochloride; monohydrate levodopa ... See more keywords