Investigation of solution‐mediated phase transformation of pranlukast DMF solvate to hemihydrate
Sign Up to like & getrecommendations! Published in 2017 at "Crystal Research and Technology"
DOI: 10.1002/crat.201700045
Abstract: Pranlukast is a potent selective cysteniyl leukotriene receptor antagonist to treat bronchial asthma and allergic rhinitis, which exists in several crystal forms. In this work, solution-mediated phase transformation process from Pranlukast DMF solvate to the… read more here.
Keywords: phase transformation; solution mediated; mediated phase; pranlukast ... See more keywords
In silico drug repurposing for the identification of potential candidate molecules against arboviruses infection.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.104668
Abstract: Arboviral diseases caused by dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses represent a major public health problem worldwide, especially in tropical areas where millions of infections occur every year. The aim of this research… read more here.
Keywords: candidate; infection; pranlukast; denv zikv ... See more keywords
Determination and correlation of solubility of pranlukast hemihydrate in five organic solvents at different temperatures and its dissolution properties
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2016.11.082
Abstract: Abstract In this study, the solubility of pranlukast hemihydrate in methanol, ethanol, 1-propanol, 2-propanol, and 1-butanol was determined at temperatures ranging from 298.15 to 323.15 K by a solid-liquid equilibrium method. The measured solubility data of… read more here.
Keywords: dissolution; pranlukast hemihydrate; pranlukast; solubility pranlukast ... See more keywords
Metabolite Dysregulation by Pranlukast in Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051520
Abstract: Mycobacterium tuberculosis has been infecting millions of people worldwide over the years, causing tuberculosis. Drugs targeting distinct cellular mechanisms including synthesis of the cell wall, lipids, proteins, and nucleic acids in Mtb are currently being… read more here.
Keywords: mycobacterium tuberculosis; metabolite dysregulation; pranlukast; tuberculosis ... See more keywords