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   Articles with "prasugrel clopidogrel" as a keyword



Comparative Effectiveness of Ticagrelor, Prasugrel, and Clopidogrel for Secondary Prophylaxis in Acute Coronary Syndrome: A Propensity Score‐Matched Cohort Study

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recommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"

DOI: 10.1002/cpt.2797

Abstract: Comparative effectiveness evaluation of newer P2Y12 inhibitors (prasugrel and ticagrelor) compared with clopidogrel after acute coronary syndrome (ACS) is limited in real‐world US populations. The objective of this study was to evaluate cardiovascular events based… read more here.

Keywords: ticagrelor; prasugrel clopidogrel; clopidogrel; comparative effectiveness ... See more keywords

Exploring the relationship of platelet aggregation function with efficacy and safety outcomes following the administration of prasugrel and clopidogrel in patients with thrombotic stroke: a post hoc analysis of PRASTRO pooled studies

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recommendations! Published in 2025 at "Journal of Thrombosis and Thrombolysis"

DOI: 10.1007/s11239-025-03093-3

Abstract: The P2Y12 receptor inhibitor prasugrel was approved for thrombotic stroke in Japan following the phase 3 clinical trials PRASTRO-I, -II, and -III. However, correlations between elevated platelet reaction unit (PRU) and ischemic event risk remain… read more here.

Keywords: prasugrel clopidogrel; analysis prastro; thrombotic stroke; pru ... See more keywords
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Effects of Ticagrelor, Prasugrel, or Clopidogrel at Steady State on Endothelial Function.

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recommendations! Published in 2018 at "Journal of the American College of Cardiology"

DOI: 10.1016/j.jacc.2018.01.027

Abstract: Ticagrelor is a nonthienopyridine direct and reversible P2Y12 platelet receptor antagonist, and unlike prasugrel or clopidogrel inhibits, at least partially, the sodium-independent equilibrative nucleoside transporter 1 [(1)][1]. This ticagrelor-mediated off-target effect has potential to improve read more here.

Keywords: prasugrel; clopidogrel steady; prasugrel clopidogrel; ticagrelor prasugrel ... See more keywords

Efficacy and Safety of Prasugrel vs Clopidogrel in Thrombotic Stroke Patients With Risk Factors for Ischemic Stroke Recurrence: A Double-blind, Phase III Study (PRASTRO-III)

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recommendations! Published in 2022 at "Journal of Atherosclerosis and Thrombosis"

DOI: 10.5551/jat.63473

Abstract: Aim: To examine the efficacy and safety of prasugrel vs clopidogrel in thrombotic stroke patients at risk of ischemic stroke. Methods: This multicenter, active-controlled, randomized, double-blind, double-dummy, parallel group study enrolled thrombotic stroke patients aged… read more here.

Keywords: efficacy; prasugrel; ischemic stroke; prasugrel clopidogrel ... See more keywords