Assessing the Clinical Treatment Dynamics of Antiplatelet Therapy Following Acute Coronary Syndrome and Percutaneous Coronary Intervention in the US.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2023.8585
Abstract: Importance A platelet ADP P2Y12 receptor (P2Y12) inhibitor plus aspirin is standard therapy for patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). Compared with clopidogrel, prasugrel and ticagrelor are associated with superior… read more here.
Keywords: prasugrel ticagrelor; bleeding risk; therapy; risk ... See more keywords
A Reconciliation Attempt of the Acute Coronary Syndrome Clinical Trials on Clopidogrel, Prasugrel, and Ticagrelor
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-06955-5
Abstract: Dear Editor, Recently, Schüpke and colleagues performed an investigator-initiated head-to-head trial on prasugrel versus ticagrelor in acute coronary syndrome [1]. We highly commend the authors for performing such study. Certainly, given the earlier trials comparing… read more here.
Keywords: ticagrelor; acute coronary; coronary syndrome; prasugrel ticagrelor ... See more keywords
Use of the VerifyNow point of care assay to assess the pharmacodynamic effects of loading and maintenance dose regimens of prasugrel and ticagrelor
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DOI: 10.1007/s11239-021-02386-7
Abstract: Prasugrel and ticagrelor are potent oral platelet P2Y12 inhibitors and are recommended over clopidogrel in patients with acute coronary syndrome (ACS). Oral platelet P2Y12 inhibitors are characterized by varying degrees of pharmacodynamic response profiles as… read more here.
Keywords: use; maintenance dose; ticagrelor; prasugrel ticagrelor ... See more keywords
One-Year Clinical Effectiveness Comparison of Prasugrel with Ticagrelor: Results from a Retrospective Observational Study using an Integrated Claims Database
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Cardiovascular Drugs"
DOI: 10.1007/s40256-017-0255-y
Abstract: BackgroundNo direct comparisons of ticagrelor and prasugrel with 1-year clinical follow-up have been reported.ObjectivesOur objective was to compare 1-year clinical outcomes among patients with acute coronary syndrome (ACS) managed with percutaneous coronary intervention (PCI) and… read more here.
Keywords: prasugrel; ticagrelor; study; prasugrel ticagrelor ... See more keywords
Clopidogrel, prasugrel, or ticagrelor use and clinical outcome in patients with acute coronary syndrome: A nationwide long-term registry analysis from 2009 to 2014.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.02.096
Abstract: BACKGROUND The beneficial use of dual antiplatelet therapy (DAPT) with acetylsalicylic acid (ASA) and P2Y12 õinhibitors has been established for patients after acute coronary syndrome (ACS). However, the optimal duration of DAPT is under debate.… read more here.
Keywords: clopidogrel; ticagrelor; patients acute; 2009 2014 ... See more keywords
Seguridad y eficacia clínica con prasugrel y ticagrelor en síndrome coronario agudo. Resultados de un registro multicéntrico en el mundo real
Sign Up to like & getrecommendations! Published in 2017 at "Revista Espanola De Cardiologia"
DOI: 10.1016/j.recesp.2017.02.007
Abstract: Resumen Introduccion y objetivos La incorporacion de los nuevos antiagregantes (NAA) prasugrel y ticagrelor a la practica clinica esta siendo erratica. Los datos del mundo real todavia son escasos. Se analizo la tendencia temporal de… read more here.
Keywords: coronario agudo; con; prasugrel ticagrelor; mundo real ... See more keywords
Optimizing selection of P2Y12 inhibiting therapy: clopidogrel, prasugrel or ticagrelor
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DOI: 10.1080/14656566.2025.2576607
Abstract: ABSTRACT Introduction Antiplatelet therapy is key for secondary prevention in patients with atherosclerotic cardiovascular disease, particularly those undergoing percutaneous coronary intervention (PCI). While aspirin has historically been the standard of care agent, oral P2Y₁₂ inhibitors… read more here.
Keywords: clopidogrel prasugrel; selection; therapy; prasugrel ticagrelor ... See more keywords
Choosing the most effective and safest P2Y12 Inhibitor for use in >70-year-old acute coronary syndrome patients: a network meta-analysis
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DOI: 10.1093/eurheartj/ehae666.3345
Abstract: Acute coronary syndrome (ACS) represents a significant health burden, especially in elderly patients. Antiplatelet therapy forms the cornerstone of medical treatment for ACS, prasugrel and ticagrelor are preferred for their rapid action and proven efficacy.… read more here.
Keywords: mortality; ticagrelor; ticagrelor clopidogrel; prasugrel ticagrelor ... See more keywords
P3842One-year efficacy and safety of prasugrel and ticagrelor in patients with Acute Coronary Syndromes: results from a prospective and multicenter ACHILLES Registry
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0683
Abstract: Prasugrel and Ticagrelor have demonstrated higher efficacy than clopidogrel in their main clinical trials for patients with Acute Coronary Syndrome (ACS). However, the long-term prognosis and different clinical characteristics related with the type of antiplatelet… read more here.
Keywords: acs; patients acute; year; prasugrel ticagrelor ... See more keywords
Head‐to‐head comparison of prasugrel versus ticagrelor in patients undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Interventional Cardiology"
DOI: 10.1111/joic.12416
Abstract: OBJECTIVES We sought to compare the efficacy and safety of prasugrel and ticagrelor in patients with coronary artery disease undergoing percutaneous coronary intervention (PCI). BACKGROUND Evidence from randomized head-to-head comparison between prasugrel and ticagrelor is… read more here.
Keywords: head; prasugrel; ticagrelor; prasugrel ticagrelor ... See more keywords
Trends of prescribing adherence of antiplatelet agents in Hong Kong patients with acute coronary syndrome: a 10-year retrospective observational cohort study
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-042229
Abstract: Objectives The objective of this study is to examine the temporal trend of antiplatelet prescribing pattern during index hospitalisation discharge in Hong Kong (HK) acute coronary syndrome (ACS) population. Design The study is a retrospective… read more here.
Keywords: aor; antiplatelet; prasugrel ticagrelor; study ... See more keywords