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   Articles with "praziquantel" as a keyword



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Efficacy of injectable praziquantel for elimination of trematode metacercariae in bluegills (Lepomis macrochirus) and quantification of parasite death by propidium iodide staining

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recommendations! Published in 2017 at "Parasitology Research"

DOI: 10.1007/s00436-017-5703-8

Abstract: Digenean trematodes have complex life cycles and control of these flatworms can be accomplished by eliminating immature parasite stages from intermediate hosts. In aquaculture systems, presence of trematode metacercariae can negatively impact fish health and… read more here.

Keywords: propidium iodide; death; iodide staining; metacercariae ... See more keywords
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Opisthorchis felineus genes differentially expressed under praziquantel shed light on the nature of tegument disruption and indicate the adaptive role of cGMP-dependent protein kinase

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recommendations! Published in 2020 at "Parasitology Research"

DOI: 10.1007/s00436-020-06764-7

Abstract: Opisthorchis felineus is a trematode flatworm that parasitises mammals, including humans, and is mainly spread throughout Eastern Europe and Western Siberia. The main drug used in treatment of opisthorchiasis and other trematode and cestode infestations… read more here.

Keywords: protein; opisthorchis felineus; disruption; nature tegument ... See more keywords
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Evaluation of Praziquantel Effectivenss After Decades of Prolonged Use in an Endemic Area in Egypt

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recommendations! Published in 2020 at "Acta Parasitologica"

DOI: 10.1007/s11686-020-00242-x

Abstract: Purpose Praziquantel (PZQ) is the preferred drug for schistomiasis treatment because of its safety. As PZQ is used for mass drug administration (MDA) in schistosomiasis endemic areas, the effectiveness of the drug, used solely for… read more here.

Keywords: endemic area; dose pzq; infection; drug ... See more keywords
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The diagnosis and treatment of urogenital schistosomiasis in Italy in a retrospective cohort of immigrants from Sub-Saharan Africa

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recommendations! Published in 2019 at "Infection"

DOI: 10.1007/s15010-019-01270-0

Abstract: ObjectivesTo evaluate ultrasound and praziquantel to, respectively, assess and reduce urogenital schistosomiasis (UGS)-associated morbidity in migrants from Sub-Saharan Africa (SSA).MethodsMigrants from SSA with UGS attending three Italian centres for tropical diseases during 2011–2016 were retrospectively… read more here.

Keywords: treatment; sub saharan; urogenital schistosomiasis; praziquantel ... See more keywords
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Effect of repeated mass drug administration with praziquantel and track and treat of taeniosis cases on the prevalence of taeniosis in Taenia solium endemic rural communities of Tanzania.

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recommendations! Published in 2017 at "Acta tropica"

DOI: 10.1016/j.actatropica.2015.10.012

Abstract: This study evaluated the effect of mass drug administration (MDA) with praziquantel administered to school-aged children (SAC) combined with 'track and treat' of taeniosis cases in the general population on the copro-antigen (Ag) prevalence of… read more here.

Keywords: prevalence taeniosis; taeniosis; taeniosis cases; track treat ... See more keywords
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Absorption and depletion of dietary administered praziquantel in greater amberjack, Seriola dumerili

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recommendations! Published in 2021 at "Aquaculture"

DOI: 10.1016/j.aquaculture.2021.736354

Abstract: Abstract The absorption and depletion of dietary administered praziquantel (PZQ) were explored in greater amberjack, Seriola dumerili, a promising farmed fish species in the Mediterranean area and elsewhere. Greater amberjack weighing 84 g were fed once… read more here.

Keywords: greater amberjack; amberjack; pzq; praziquantel ... See more keywords
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An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: The case of praziquantel.

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recommendations! Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.05.053

Abstract: Praziquantel, a BCS II class anthelmintic drug used for the treatment of schistosome infections, was coground in a vibrational mill with different polymers (linear and crosslinked povidone, copovidone and sodium starch glycolate). An explorative analysis… read more here.

Keywords: vibrational mill; explorative analysis; formulation variables; process ... See more keywords
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Solid dispersion of praziquantel enhanced solubility and improve the efficacy of the schistosomiasis treatment

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recommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2018.03.009

Abstract: Abstract Praziquantel (PZQ) is an anthelmintic of choice in the treatment of schistosomiasis. Solvent evaporation technique produced three different Solid Dispersions (SD) (drug: polymer, w/w) with sodium alginate (ALG) or carboxymethylcellulose (CMC). Characterization was done… read more here.

Keywords: schistosomiasis; solid dispersion; treatment; dispersion praziquantel ... See more keywords
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A genetic TRP down the channel to praziquantel resistance.

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recommendations! Published in 2022 at "Trends in parasitology"

DOI: 10.1016/j.pt.2022.02.006

Abstract: The anthelmintic praziquantel (PZQ) is an essential tool in controlling schistosomiasis, so reports of reduced PZQ efficacy are of great public health concern. Le Clec'h et al. recently identified a gene responsible for PZQ resistance… read more here.

Keywords: praziquantel resistance; resistance; trp channel; genetic trp ... See more keywords
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The anthelminthic drug praziquantel is a selective agonist of the sensory transient receptor potential melastatin type 8 channel

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recommendations! Published in 2017 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2017.10.012

Abstract: &NA; Praziquantel is the most effective anthelminthic drug for the treatment of schistosomiasis, an infectious disease caused by the platyhelminth Schistosoma mansoni. While praziquantel is known to trigger calcium influx into schisostomes, followed by spastic… read more here.

Keywords: anthelminthic drug; drg neurons; drug; praziquantel ... See more keywords
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Pharmacokinetics of a novel spot-on formulation of praziquantel for dogs.

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recommendations! Published in 2017 at "Veterinary parasitology"

DOI: 10.1016/j.vetpar.2017.04.022

Abstract: Praziquantel (PZQ) is an anthelmintic drug used both in humans and animals that can be administered through various routes. There are transdermal formulations for cats, but only oral or subcutaneous dosage forms for dogs. Given… read more here.

Keywords: concentration; spot formulation; time; praziquantel ... See more keywords