Articles with "prazosin" as a keyword



0667 A digital prescription therapeutic device to treat nightmare disorders: A case series

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Published in 2023 at "SLEEP"

DOI: 10.1093/sleep/zsad077.0667

Abstract: Introduction: Nightmare disorder and post-traumatic stress disorder (PTSD)-associated nightmares can be treatment-resistant in many patients. There are no recommended treatments for these conditions currently. Methods: NightWare is a novel FDA-approved class II medical device which… read more here.

Keywords: nightmare; series; case series; cgi ... See more keywords

The effect of prazosin on outcome in feline urethral obstruction

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Published in 2017 at "Journal of Veterinary Emergency and Critical Care"

DOI: 10.1111/vec.12611

Abstract: Objective To determine whether prazosin administration following urethral obstruction (UO) reduces the risk for recurrent urethral obstruction (rUO) or lower urinary tract signs, and to document adverse effects associated with prazosin use in cats. Design… read more here.

Keywords: urinary tract; prazosin; tract signs; lower urinary ... See more keywords

Effect of prazosin on feline recurrent urethral obstruction

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Published in 2021 at "Journal of Feline Medicine and Surgery"

DOI: 10.1177/1098612x211001283

Abstract: Objectives The aim of this study was to determine if male cats treated with 7 days of prazosin following relief of urethral obstruction (UO) experienced decreased rates of recurrent urethral obstruction (rUO) within 30 days… read more here.

Keywords: feline; prazosin; study; ruo ... See more keywords

Prazosin administration increases the rate of recurrent urethral obstruction in cats: 388 cases.

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Published in 2022 at "Journal of the American Veterinary Medical Association"

DOI: 10.2460/javma.21.10.0469

Abstract: OBJECTIVE To determine if prazosin administration decreased the rate of recurrent urethral obstruction (rUO) before hospital discharge and within 14 days. ANIMALS 388 cats with urethral obstruction. PROCEDURES Veterinarians who either always or never prescribed… read more here.

Keywords: prazosin administration; prazosin; rate; urethral obstruction ... See more keywords

A sex-sensitive LC-MS/MS method with isotopic internal standard for prazosin bioequivalence: bridging precision medicine and generic drug policy in China

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Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1592731

Abstract: Objective To develop a rapid, sensitive, and high-throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for prazosin quantification in human plasma, validate its application in bioequivalence studies, and investigate sex-specific pharmacokinetic differences in a Chinese population.… read more here.

Keywords: prazosin; isotopic internal; internal standard; sex ... See more keywords

Case series: Continued remission of PTSD symptoms after discontinuation of prazosin

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Published in 2023 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2023.1172754

Abstract: Post-traumatic stress disorder is a debilitating chronic illness that affects 6 out of 100 adults after a severe trauma. The alpha-adrenergic antagonist prazosin, which is prescribed off-label for flashbacks and nightmares due to trauma, is… read more here.

Keywords: case series; prazosin; discontinuation prazosin; discontinuation ... See more keywords

Muting Bacterial Communication: Evaluation of Prazosin Anti-Quorum Sensing Activities against Gram-Negative Bacteria Pseudomonas aeruginosa, Proteus mirabilis, and Serratia marcescens

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Published in 2022 at "Biology"

DOI: 10.3390/biology11091349

Abstract: Simple Summary Bacterial infections are considered one of the main challenges to global health. Bacterial virulence is controlled by interplayed systems to regulate bacterial invasion and infection in host tissues. Quorum sensing (QS) plays a… read more here.

Keywords: anti virulence; prazosin; production; mirabilis ... See more keywords

Method Development for the Simultaneous Estimation of Prazosin and Polythiazide by UPLC Using QbD Approach

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Published in 2025 at "Indian Journal of Pharmaceutical Education and Research"

DOI: 10.5530/ijper.20250020

Abstract: Introduction: Prazosin is a quinazoline derivative and a selective antagonist of the α1 adrenergic receptor. The atomic structure is C 19 H 21 N 5 O 4 and its molecular weight is 383.41 Prazosin is… read more here.

Keywords: prazosin; method; method development; development simultaneous ... See more keywords