Significant Improvement in Rat Kidney Cold Storage Using UW Organ Preservation Solution Supplemented With the Immediate-Acting PrC-210 Free Radical Scavenger
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DOI: 10.1097/txd.0000000000001032
Abstract: Background. Ischemia-reperfusion injury, including injury from warm- and cold-ischemia (CI) organ storage, remains a significant problem for all solid organ transplants. Suppressing CI damage would reduce delayed graft function and increase the donor organ pool… read more here.
Keywords: rat; prc 210; injury; kidney ... See more keywords
Significant Reduction of Total-Body Irradiation-Induced Death in Mice Treated with PrC-210 24 Hours Postirradiation
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DOI: 10.1667/rade-22-00036.1
Abstract: The search for radiation countermeasures that can serve as: i. a pre-exposure agent to protect against subsequent irradiation, and/or ii. a post-exposure agent to mitigate the development of Acute Radiation Syndrome after radiation exposure, remains… read more here.
Keywords: postirradiation; acute radiation; radiation; mice ... See more keywords
Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats
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DOI: 10.3390/biom11071054
Abstract: Allograft kidney transplantation, which triggers host cellular- and antibody-mediated rejection of the kidney, is a major contributor to kidney damage during transplant. Here, we asked whether PrC-210 would suppress damage seen in allograft kidney transplant.… read more here.
Keywords: kidney damage; prc 210; inflammation; transplant ... See more keywords