Targeted disruption of PRC1.1 complex enhances bone remodeling
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DOI: 10.1038/s41467-025-59638-w
Abstract: Polycomb repressive complexes (PRCs) are pivotal epigenetic regulators that preserve cell identity by restricting transcription responses to sub-threshold extracellular signals. Their roles in osteoblast function and bone formation remain unclear. Here in aging osteoblasts, we… read more here.
Keywords: prc1; bone remodeling; prc1 complex; bone formation ... See more keywords