Articles with "prc2 complex" as a keyword



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Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups

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Published in 2021 at "Leukemia"

DOI: 10.1038/s41375-021-01379-y

Abstract: Sequencing studies have shed some light on the pathogenesis of progression from smouldering multiple myeloma (SMM) and symptomatic multiple myeloma (MM). Given the scarcity of smouldering samples, little data are available to determine which translational… read more here.

Keywords: molecular subgroups; importance prc2; prc2 complex; myeloma ... See more keywords

Abstract We136: HnRNPA1 Modulates Expression of Myogenic Differentiation Factors by Maintenance of Ppp1r1b - lncRNA /PRC2 Complex Integrity

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Published in 2024 at "Circulation Research"

DOI: 10.1161/res.135.suppl_1.we136

Abstract: Objective: HnRNPA1 is an important member of the HNRNP family, serves multiple functions. The long noncoding RNA Ppp1r1b is a key regulator of myogenesis in cardiac and skeletal muscle development. This study aimed to investigate… read more here.

Keywords: hnrnpa1; ppp1r1b; ppp1r1b lncrna; lncrna prc2 ... See more keywords