Peroxiredoxin 4 suppresses anoikis and augments growth and metastasis of hepatocellular carcinoma cells through the β-catenin/ID2 pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cellular Oncology"
DOI: 10.1007/s13402-019-00460-0
Abstract: Peroxiredoxin 4 (PRDX4) has been reported to play a dual role in the progression of hepatocellular carcinoma (HCC). As yet, however, the underlying molecular mechanism has not been fully elucidated. We examined the effects of… read more here.
Keywords: prdx4; hcc cells; anchorage independent; metastasis ... See more keywords
Oxidation state of peroxiredoxin 4 in lungs from patients with pulmonary fibrosis and mouse models of fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.014
Abstract: Rationale Every year 34,000 people in the United States are diagnosed with Idiopathic Pulmonary Fibrosis (IPF). The average survival time for these patients is only 3-5 years after diagnosis. Recently we have shown that the… read more here.
Keywords: mouse models; fibrosis; prdx4; peroxiredoxin ... See more keywords
Suppression of PRDX4 inhibits cell proliferation and invasion of ectopic endometrial stromal cells in endometriosis
Sign Up to like & getrecommendations! Published in 2020 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2020.1768369
Abstract: Abstract Oxidative stress (OS) has been proposed to play a role in the development of EMs. Peroxiredoxins are a family of antioxidant proteins that exhibit peroxidase activity in a thioredoxin-dependent manner, protecting cells against OS.… read more here.
Keywords: invasion; prdx4; stromal cells; endometrial stromal ... See more keywords