Administration of the sigma-1 receptor agonist PRE-084 at emerging adulthood, but not at early adolescence, attenuated ethanol-induced conditioned taste aversion in female rats
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DOI: 10.1016/j.neulet.2022.136585
Abstract: Ethanol-induced conditioned taste aversion (CTA) is greater in late adolescence or young adulthood than in early adolescence. The role of the sigma receptor system in this age-related difference has not been extensively explored, particularly in… read more here.
Keywords: adolescence; sigma; early adolescence; pre 084 ... See more keywords
S1R agonist modulates rat platelet eicosanoid synthesis and aggregation.
Sign Up to like & getrecommendations! Published in 2021 at "Platelets"
DOI: 10.1080/09537104.2021.1981843
Abstract: Sigma-1 receptor (S1R) is detected in different cell types and can regulate intracellular signaling pathways. S1R plays a role in the pathomechanism of diseases and the regulation of neurotransmitters. Fluvoxamine can bind to S1R and… read more here.
Keywords: aggregation; s1r agonist; pre 084; eicosanoid synthesis ... See more keywords